Sökning: "stem cells differentiation"

Visar resultat 1 - 5 av 33 uppsatser innehållade orden stem cells differentiation.

  1. 1. PAMPaR: Parallel Analysis of miRNAs, Proteins and RNAs. Dynamic Profiles of miRNAs, mRNAs and Specific Proteins in Mouse Embryonic Stem Cells Differentiating into Neural Precursors

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Amelie Carlström; [2023]
    Nyckelord :PAMPaR; SPARC; Proximity extension assay; Neuronal differentiation; Mouse embryonic stem cells; PAMPaR; SPARC; Proximity extension assay; Neuronal differentiering; embryonala musstamceller;

    Sammanfattning : MikroRNA-molekyler (miRNA) är viktiga icke-kodande RNA-molekyler för post-transkriptionell reglering av proteinkodande gener. De har även effekter på många cellulära processer såsom differentiering. De biosyntetiska reaktioner som skapar miRNA involverar proteiner som själva regleras av miRNA. LÄS MER

  3. 2. The impact of human relevant mixture of contaminants on the development of human adipocytes

    Uppsats för yrkesexamina på grundnivå, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Annika Jansson; [2023]
    Nyckelord :;

    Sammanfattning : The objective of this project was to investigate how organic anthropogenic chemicals (OCs) effect the differentiation of adipocytes in the human body. The objective is also to contribute to novel research in how groups of chemicals in our surrounding affect us. LÄS MER

  4. 3. The effect of calcium silicate-based cements on viability and differentiation of human stem cells from the dental apical papilla. : Future aspects in endodontic regeneration.

    Master-uppsats, Umeå universitet/Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM); Umeå universitet/Tandläkarutbildning

    Författare :Lahood Abdalla; Bagir Soltani; [2023]
    Nyckelord :MTA; Biodentine; SCAP; Regenerativ endodonti; endodonti; traumatiserade tänder; tänder; unga tänder;

    Sammanfattning : Introduction: Pulp necrosis in immature permanent teeth stops root development and may lead to higher risk of cervical fractures and a challenging treatment. Regenerative endodontic treatment (RET) aims to continue tooth development and implies the use of calcium silicate-based cements, such as Mineral trioxide aggregate (MTA) and Biodentine to seal the root canal. LÄS MER

  5. 4. Impact of BPA, BPF and Mixture N1 on DNA-Methylation of GRIN2B and NR3C1 during human neuroprogenitor cell differentiation

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Fysiologi och miljötoxikologi

    Författare :Franziska Sophie Richter; [2023]
    Nyckelord :Epigenetics; Endocrine disrupting chemicals; DNA methylation; EDCs; Mixture effects; BPA; BPF; Mixture N1;

    Sammanfattning : Endocrine disrupting chemicals (EDCs) are ubiquitous and their adverse impact on nature, wildlife and humans is extensively researched. We are constantly exposed to EDCs, such as the widespread and extensively researched Bisphenol A, as well as its substitute Bisphenol F, which is coming into wider use, even though it is much less is researched and limited information is available about its endocrine effects. LÄS MER

  7. 5. Hypoxia and hematopoietic stem cell control with the substance Adaptaquin : An evaluation of hematopoietic stem cell’s proliferation and differentiation in artificially induced hypoxia

    Kandidat-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Jens Christiansen; [2023]
    Nyckelord :Adaptaquin; Flow cytometry; Hematopoietic stem cells; Hypoxia; Hypoxia inducible factor; Prolyl hydroxylase; Adaptaquin; Flödescytometri; Hematopoetiska stamceller; Hypoxi; Hypoxi inducerande faktor; Prolylhydroxylas;

    Sammanfattning : Hematopoietic stem cells (HSCs) have historically been difficult to maintain ex vivo with many attempts to culture them in vitro by mimicking their natural biological environment. Providing a hypoxic environment is one way to achieve this goal and can be performed by using hypoxia stimulating compounds that inhibits the degradation of HIF1a which plays an important role in regulating hypoxia. LÄS MER