Sökning: "Cysteine proteases"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden Cysteine proteases.

  1. 1. Studies of broad-spectrum inhibitors against main protease of SARS-CoV-2 and other Coronaviruses

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Alexandra Stanciu; [2023]
    Nyckelord :human coronavirus 229E; SARS-CoV-2; main protease; nirmatrelvir; GC-376; compound 19;

    Sammanfattning : Coronaviruses have caused three large outbreaks in the past century. The most recent one, also still ongoing, is represented by the SARS-CoV-2/Covid-19 pandemic. Efforts have been taken to develop efficient vaccines and antivirals and one of the major virus-based targets in drug development is represented by the main protease of these viruses. LÄS MER

  3. 2. Selective Inhibition of Metacaspase 4 in Arabidopsis Thaliana  

    Master-uppsats, Umeå universitet/Kemiska institutionen

    Författare :Thilde Andersson; [2021]
    Nyckelord :;

    Sammanfattning : Metacaspases are a recently discovered family of cysteine-dependent proteases present in plants, fungi, and lower eukaryotes. They are believed to be involved in regulated cell death in non-metazoan cells, but little is known about their distinct functional properties. LÄS MER

  4. 3. Recombinant production of the Giardia intestinalis cysteine protease CP10217 in Pichia pastoris

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för cell- och molekylärbiologi

    Författare :Sofia Gräsberg; [2019]
    Nyckelord :;

    Sammanfattning : Giardia intestinalis is one of the leading causes of diarrheal diseases, affecting about 280 million people every year. By characterizing the virulence factors of G. intestinalis, new drug targets can be found to treat giardiasis. LÄS MER

  5. 4. Host cell response upon exposure to Giardia intestinalis glycoproteins in vitro

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Inês Neves; [2018]
    Nyckelord :;

    Sammanfattning : Giardia intestinalis is an intestinal parasite responsible for a burden of millions of infections worldwide yearly, especially in children. Although the disease affects millions there is poor understanding of the pathophysiology of the parasite and how it causes disease. LÄS MER

  7. 5. Uttryck av cysteineproteaser HRV 3C, sortase A och TEV på ytan av prokaryota värdceller

    Master-uppsats, KTH/Skolan för bioteknologi (BIO)

    Författare :Therese Nilsson; [2015]
    Nyckelord :Cysteine proteases; E.coli display; FACS; HRV 3C; sortase A; Staphylococcal display; TEV;

    Sammanfattning : Proteases are important enzymes in the biotechnology due to their specific cleavage of substrates. HRV 3C, sortase A and TEV are some examples of cysteine proteases which become more of use lately in applications as removal of affinity tags (3C/TEV) and labelling of proteins (sortase). LÄS MER