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1. 1. Epigenetic Regulation of Mitochondrial DNA

   Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

   Författare :Jennie Johansson; [2020]
   Nyckelord :Acetylation; Epigenetics; Heteroplasmy; Methylation; Mitochondrial haplotype; Mitochondrion; Non coding RNA; Phosphorylation;

   Sammanfattning : This mini-review investigates and compiles the latest knowledge regarding epigenetic changes on the mammalian mitochondrial DNA and its proteins. Methylation of the DNA, acetylation of the proteins and silencing of genes by short non-coding RNAs are the main epigenetic changes known today to affect mitochondrial DNA, mostly leading to repression. LÄS MER