Sökning: "Interactomes"

Hittade 2 uppsatser innehållade ordet Interactomes.

  1. 1. The Effect of Interactive Selection on Personalized Drug Prediction Using Interactomes : Examination of Parameters Impacting Drug Treatment Rankings from Network Models for Covid-19 Patients

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Cornelia Torell; [2023]
    Nyckelord :Precision Medicine; Pharmacogenomics; Biomarkers; Covid-19; Digital Twins; Network Modeling; Interactomes; Protein-Protein Interaction Networks; Differentially Expressed Genes; Principal Coordinate Analysis; Precisionsmedicin; Farmakogenetik; Biomarkörer; Covid-19; Digitala tvillingar; Nätverksmodellering; Interaktom; Proteininteraktionsnätverk; Sjukdomsrelaterade gener; Principalkoordinatanalys;

    Sammanfattning : Patients not responding to therapy as expected is one of the most pressing healthcare concerns of today. It causes economical, medical and societal issues along with suffering for patients. This project aimed to address this problem and evaluate how to find the best suited drug treatments for individual patients to treat Covid-19. LÄS MER

  3. 2. Predicting safe drug combinations with Graph Neural Networks (GNN)

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Amirhossein Amanzadi; [2021]
    Nyckelord :Drug Combination; Polypharmacy Side Effects; Graph Neural Networks;

    Sammanfattning : Many people - especially during their elderly - consume multiple drugs for the treatment of complex or co-existing diseases. Identifying side effects caused by polypharmacy is crucial for reducing mortality and morbidity of the patients which will lead to improvement in their quality of life. LÄS MER