Sökning: "Precisionsmedicin"

Visar resultat 1 - 5 av 8 uppsatser innehållade ordet Precisionsmedicin.

  1. 1. Biological Age and Risk of Developing Alzheimer's Disease and Related Dementias

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Karolina Gustavsson; [2024]
    Nyckelord :Biological age BA ; PhenoAge; Klemera Doubal Method KDM ; Homeostatic Dysregulation HD ; Alzheimer’s disease and related dementias ADRD ; Biologisk ålder; PhenoAge; Klemera Doubal-metod; Homeostatic Dysregulation HD ; Alzheimers sjukdom och relaterade demenssjukdomar ADRD ;

    Sammanfattning : Biologisk ålder (BA) har nyligen fått ökad uppmärksamhet att fördjupa förståelsen kring åldersrelaterade sjukdomar och dess behandlingar, eftersom åldersrelaterade förändringar utgör en grundläggande gemensam nämnare för dessa tillstånd. Medan kronologisk ålder (CA) mäts i år, kan biologisk ålder (BA) mätas på många olika sätt. LÄS MER

  3. 2. Systematic Multi-Parametric Analysis of Acute Myeloid Leukemia (AML) Flow Cytometry Drug Screens using Flowty

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Augusta Jensen; [2023]
    Nyckelord :Acute myeloid leukemia; AML; cellular subpopulations; data analysis; precision medicine; Flowty; applied microbiology; Biology and Life Sciences;

    Sammanfattning : Acute myeloid leukemia (AML) is a heterogeneous disease, making it difficult to treat. The standard treatment is intensive chemotherapy and has not changed in 40 years. However, recently new drugs and as less intensive treatment regimens have been approved in the US and in Europe. However. LÄS MER

  4. 3. The Effect of Interactive Selection on Personalized Drug Prediction Using Interactomes : Examination of Parameters Impacting Drug Treatment Rankings from Network Models for Covid-19 Patients

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Cornelia Torell; [2023]
    Nyckelord :Precision Medicine; Pharmacogenomics; Biomarkers; Covid-19; Digital Twins; Network Modeling; Interactomes; Protein-Protein Interaction Networks; Differentially Expressed Genes; Principal Coordinate Analysis; Precisionsmedicin; Farmakogenetik; Biomarkörer; Covid-19; Digitala tvillingar; Nätverksmodellering; Interaktom; Proteininteraktionsnätverk; Sjukdomsrelaterade gener; Principalkoordinatanalys;

    Sammanfattning : Patients not responding to therapy as expected is one of the most pressing healthcare concerns of today. It causes economical, medical and societal issues along with suffering for patients. This project aimed to address this problem and evaluate how to find the best suited drug treatments for individual patients to treat Covid-19. LÄS MER

  5. 4. Prediction of Persistence to Treatment for Patients with Rheumatoid Arthritis using Deep Learning

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Serkan Arda Yilal; [2023]
    Nyckelord :Variational Autoencoders; Rheumatoid Arthritis; Precision Medicine; Treatment Prediction; Deep Learning; Supervised Learning; Rheumatoid Artrit; Precisionsmedicin; Behandlingsförutsägelse; Djupinlärning; Övervakat lärande;

    Sammanfattning : Rheumatoid Arthritis is an inflammatory joint disease that is one of the most common autoimmune diseases in the world. The treatment usually starts with a first-line treatment called Methotrexate, but it is often insufficient. One of the most common second-line treatments is Tumor Necrosis Factor inhibitors (TNFi). LÄS MER

  7. 5. Improving Usability of Bioinformatics Software with an Integrated Web Tool System for Cancer Diagnostics

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Solbritt Gateman; [2023]
    Nyckelord :Web development; bioinformatics pipelines; precision medicine; user-centred design; interface design;

    Sammanfattning : Precision cancer medicine is an area of research that involves complex bioinformatics software for the clinical analysis pipelines that sequencing data is passed through. A research team at Karolinska Institutet (KI) is running clinical trials to test new methods of precision cancer medicine and is working on creating a new web application that will be integrated with their two existing applications to aid bioinformaticians in their work of running pipelines and producing clinical reports for the hospitals. LÄS MER