Sökning: "anticancer treatment"

Visar resultat 6 - 8 av 8 uppsatser innehållade orden anticancer treatment.

  1. 6. Exploring the effects of platinum compounds on RNA, adduct formation, thermal melting properties and siRNA down regulation capacity of gene targets associated

    Master-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Alak Al Shiekh; [2012]
    Nyckelord :Proteinvetenskap; Chemistry;

    Sammanfattning : Since its discovery, RNA interference (RNAi) has turned into an invaluable research tool for regulating gene expression. Furthermore, this naturally occurring phenomenon in mammalian cells is of interest in cancer research, both as a possible therapeutic approach and a target for cancer treatment. LÄS MER

  2. 7. The screening for novel proteasome inhibitors as a treatment of cancer using IncuCyte FLR and fluorometric microculture cytotoxicity assay.

    Kandidat-uppsats, Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Olga Golovko; [2011]
    Nyckelord :Anticancer drug development; proteasome inhibition; chemotherapy; image-based screening assay; FMCA.;

    Sammanfattning : The problem of finding targeted medicine is a central problem in chemotherapy. From this point of view the ubiquitin-proteasome system is a highly promising object in the pharmaceutical approach. Proteasome plays a critical role in cellular protein degradation, cell cycle and apoptosis regulation. LÄS MER

  3. 8. Do the new signal transduction modulators have activity in vitro in tumor cells from ovarian carcinoma and lymphoma?

    Kandidat-uppsats, Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Desiré Lundin; [2005]
    Nyckelord :Anticancer drug development; ovarian carcinoma; lymphoma; FMCA; cytotoxic drugs; in vitro assay;

    Sammanfattning : During the last decades, chemotherapy with cytotoxic drugs has played a significant role in cancer therapy. It’s important to develop new anticancer drugs, and drug sensitivity testing in vitro can be used to find the right diagnosis for the newly developed substances. LÄS MER