Sökning: "bioinformatics pipeline"

Visar resultat 1 - 5 av 38 uppsatser innehållade orden bioinformatics pipeline.

1. 1. SubKluster: Novel method to bin scaffolds from cereal genomes into subgenomes using substring frequency analysis

   Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

   Författare :Victor Kalbskopf; [2023]
   Nyckelord :Biology and Life Sciences;

   Sammanfattning : The genome of the Belinda variety of the hexaploid oat (Avena sativa) has recently been sequenced and assembled. This project aims to improve the assembly by clustering the thousands of scaffolds into their three ancestral subgenomes using Principle Component Analysis (PCA) of kmer and repeat-element frequencies. LÄS MER

3. 2. CRISPR-Drawr, a tool to design mutagenic primer

   Magister-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Larsson Torbjörn; [2023]
   Nyckelord :Integrated CRISPR design; new score method; short open reading frames; functional screening; bioinformatics;

   Sammanfattning : Short open reading frames (sORFs) are codon sequences with a start and stop codon within atmost 100 codons. Cells produce many transcripts from them and some sORFs have been found to have function. sORFs have been associated with embryogenesis, myogenesis, immunity and various diseases including cancers. LÄS MER

4. 3. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

   Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

   Författare :Yi Su; [2023]
   Nyckelord :Biology and Life Sciences;

   Sammanfattning : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. LÄS MER

5. 4. Developing a reproducible bioinformatics workflow for canine inherited retinal disease

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Melina Toni Marie Martin; [2023]
   Nyckelord :CanFam4; Nextflow; Inherited Retinal Degeneration; dog; whole-genome sequencing; bioinformatics;

   Sammanfattning : Inherited Retinal Degenerations (IRDs) are a heterogenous group of diseases which lead to vision impairment and can be found both in humans and in dogs. About 1 in 1,380 humans is estimated to suffer from an autosomal recessive IRD, which would be 5.5 million people worldwide, and many more are estimated to be unaffected carriers. LÄS MER

7. 5. Improving Usability of Bioinformatics Software with an Integrated Web Tool System for Cancer Diagnostics

   Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

   Författare :Solbritt Gateman; [2023]
   Nyckelord :Web development; bioinformatics pipelines; precision medicine; user-centred design; interface design;

   Sammanfattning : Precision cancer medicine is an area of research that involves complex bioinformatics software for the clinical analysis pipelines that sequencing data is passed through. A research team at Karolinska Institutet (KI) is running clinical trials to test new methods of precision cancer medicine and is working on creating a new web application that will be integrated with their two existing applications to aid bioinformaticians in their work of running pipelines and producing clinical reports for the hospitals. LÄS MER