Sökning: "drug screening"

Visar resultat 36 - 40 av 63 uppsatser innehållade orden drug screening.

  1. 36. Screening of large collection of compounds for anti-human parainfluenza virus type-2 activity and evaluation of hit compounds

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Vijeta Rai; [2017]
    Nyckelord :Screening; Virucidal activity; Selective index; Cytopathic effect;

    Sammanfattning : Human parainfluenza virus type-2 (HPIV-2) is a highly contagious respiratory pathogen that can cause severe respiratory disease known as laryngotracheobronchitis or croup-like disease in children. No specific vaccine or an antiviral drug is currently approved for treatment of HPIV-2 infections. LÄS MER

  3. 37. Classification of High Content Screening Data by Deep Convolutional Neural Networks

    Kandidat-uppsats, Uppsala universitet/Institutionen för informationsteknologi

    Författare :Karl-Johan Leuchowius; [2017]
    Nyckelord :;

    Sammanfattning : In drug discovery, high content screening (HCS) is an imaging-based method forcell-based screening of large libraries of drug compounds. HCS generates enormous amounts of images that need to be analysed and quantified by automated image analysis. LÄS MER

  4. 38. Bringing 3D Bioprinting to the Market; Agile marketing, rapid product development and strategic alliances

    Master-uppsats, Göteborgs universitet/Graduate School

    Författare :Erik Gatenholm; [2016-12-19]
    Nyckelord :3D Bioprinting; CELLINK; Agile Marketing; Strategic Alliances; Disruptive Technology;

    Sammanfattning : 3D bioprinting technology is an emerging technology with a potential to revolutionize the medical field as it has a capability to biofabricate living tissue and organs using a patient’s own cells in conjunction with different biomaterials. This disruptive technology is in an early stage and innovators and early adopters stepwise improve the performance of the technology as it continuously grow. LÄS MER

  5. 39. Synthesis of Substituted Pyrrolidines

    Master-uppsats, KTH/Skolan för kemivetenskap (CHE)

    Författare :Olof Sjölin; [2016]
    Nyckelord :Pyrrolidines; Multistep synthesis; Fragment-based drug design; Drug discovery; Organic chemistry;

    Sammanfattning : The task of medicinal chemists in a drug discoveryproject is to synthesize/design analogues to the screening hits, simultaneouslyincreasing target potency and optimizing the pharmacological properties.  This requires a wide selection of moleculesto be synthesized, where both synthetic feasibility and price of startingmaterials are of great importance. LÄS MER

  7. 40. Icke-odlingsbara bakterier : är det framtiden för antibiotikautvecklingen?

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Andreas Frank; [2016]
    Nyckelord :antibiotikautveckling; antibiotikaresistens; isolation chip; iChip; teixobactin; antibiotic development; antibiotic resistance;

    Sammanfattning : Ända sedan genombrottet för antibiotika i början av 1940-talet, har resistensutveckling varit känd och redan 1945 varnades allmänheten, genom Alexander Fleming, för vad som skulle kunna hända. Trots detta har problemen ökat lavinartat dels till följd av oförsiktig användning och otydliga riktlinjer, och dels som en konsekvens av allt färre nya antibiotika på marknaden. LÄS MER