Sökning: "extracellular matrix"

Visar resultat 6 - 10 av 52 uppsatser innehållade orden extracellular matrix.

  1. 6. Role Of The EmaA Adhesin In Aggregatibacter aphrophilus Serum Resistance

    Master-uppsats, Umeå universitet/Tandläkarutbildning

    Författare :wourod Shamoun; Amal Alhaddad; [2022]
    Nyckelord :;

    Sammanfattning : ABSTRACT:  Background: Aggregatibacter aphrophilus is a Gram-negative bacterium that is considered to be highly virulent in endocarditis and cerebral abscesses but has low virulence when it comes to periodontitis. One important mechanism for the virulence of A. LÄS MER

  3. 7. Development of Microfluidic 3D Cell Culture with a Nanocellulose-Based Scaffold for Spheroid Formation as a Potential Tool for Drug Screening

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Sara Payande; [2022]
    Nyckelord :3D cell culture; Scaffold; Microfluidics; Layer-by-Layer; Cellulose Nanofibrils; Spheroids; HepG2; 3D cellodling; Matris; Mikrofluidik; Layer-by-Layer; Cellulosa Nanofibriller; Sfäroider; HepG2;

    Sammanfattning : Abstract  Lack of clinical relevance is assumed to be the main reason behind the high failure rate of medical drugs in the very initial phases of clinical trials. Clinical relevance is difficult to achieve with current tools as they lack the biological and physiological cues found in vivo. LÄS MER

  4. 8. Hyaluronic Acid Hydrogel as a Scaffold for Cells’ Encapsulation

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för materialvetenskap

    Författare :Susanna Wärmegård; [2022]
    Nyckelord :hyaluronic acid; hydrogel; 3D cell culture;

    Sammanfattning : Hydrogels are high water-content polymers that mimic the extracellular matrix of cells. The polymers can have many sources and be of natural origin from the extracellular matrix (ECM) of cells or be synthetically derived. LÄS MER

  5. 9. Extracellular vesicles (EVs):roles in cell proliferation and transcriptomic analysis of HUVEC receiving cancerderived EVs

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Benyapa Tangruksa; [2021]
    Nyckelord :;

    Sammanfattning :  Extracellular vesicles (EVs) are released by almost  all types of cells. EVs play an    important role in cell-to-cell communication by sending biomolecules such as mRNAs to    other cells via endocytosis. LÄS MER

  7. 10. Validation of a 3D culture model for toxicity studies in malignant and non-cancerous cells

    Master-uppsats, Lunds universitet/Institutionen för immunteknologi

    Författare :Kajsa Andreasson Dahlgren; [2021]
    Nyckelord :Dose-response; potency; in vitro; 2D model; 3D model; cancer; MEK inhibitor; trametinib; A549; LL47; Western blot; Biology and Life Sciences;

    Sammanfattning : Cancer is a widespread and commonly fatal disease in constant need of new treatments. Traditionally, new pharmaceuticals have been tested in 2D models. This is not ideal, as 2D environments do not reflect the in vivo milieu of the cells. LÄS MER