Sökning: "extracellular matrix"

Visar resultat 11 - 15 av 52 uppsatser innehållade orden extracellular matrix.

  1. 11. Identification of changes in biomarkers relevant for breast cancer biology occurring in a novel 3D-Biosilk model

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Emmy Ståhl; [2021]
    Nyckelord :3D-Biosilk; breast cancer; 3D cell culture; recombinant spider silk; ZO-1; 3D-Biosilk; bröstcancer; 3D cellkultur; rekombinant spindeltråd; ZO-1;

    Sammanfattning : Bröstcancer är den vanligaste formen av cancer som drabbar kvinnor. Det är en heterogen och komplex sjukdom som består av flera undergrupper, var och en med distinkt morfologi och kliniska implikationer [1]. För att modellera och studera cellbiologi, vävnadsmorfologi, molekylära mekanismer och läkemedels effekter används cellkulturer [2]. LÄS MER

  3. 12. Interactions between Rho-ROCK signaling and the tumor microenvironment in neuroblastoma

    Master-uppsats, Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Adena Pepich; [2021]
    Nyckelord :cancer and oncology; pediatric cancer; neuroblastoma; rho ROCK signaling; rho-associated kinases; tumor microenvironment; cytotoxic T cells; neuroblastom; pediatrik onkologi; rho-kinaser;

    Sammanfattning : Neuroblastoma is a childhood cancer of the peripheral sympathetic nervous system, emerging from cells of the neural crest. In Sweden, neuroblastoma accounts for 20 cases out of all, 300-350, pediatric cancer cases each year (Barncancerfonden 2019, Turup on behalf of Cancer Centrum 2019). LÄS MER

  4. 13. 3D Bioprinting Meniscus for Future Tissue Replacement in Osteoarthritis Affected Knee Joints

    H-uppsats,

    Författare :Ida Pettersson; Amanda Olsson Widjaja; [2020-06-22]
    Nyckelord :Alginate; Articular Cartilage; Bioink; Induced Pluripotent Stem Cells; Meniscus; Nanofibrillated Cellulose; Osteoarthritis; Screening; 3D Bioprinting;

    Sammanfattning : Progressive cartilage defects in human knee joints are a worldwide health issue that exposes a great burden on society as well as on single individuals. Sudden traumas to the knees can induce tears in the structures of the joints such as the articular cartilage and the meniscus. LÄS MER

  5. 14. The Effects of Mast Cell Proteases on Human Lung Cells Population

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Xinran Zhao; [2019]
    Nyckelord :asthma; primary cell; tryptase; chymase;

    Sammanfattning : Asthma is a devastating disease characterized by airway obstruction, inflammation, and bronchial hyperreactivity. Previous studies have implicated mast cells in the pathology of asthma, yet the role and function of mast cells in the early stage of human asthma development cannot be investigated in vivo for ethical reasons. LÄS MER

  7. 15. Effects of Different Laminins on Human Neural Progenitor Cells Cultured in 3D Electrospun Fibers

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Karl Vesterlund; [2019]
    Nyckelord :two-dimensional; three-dimensional; Alamar Blue; cell culture; drug development; extra-cellular matrix; electrospinning; immunocytochemistry; laminin; polycaprolactone; polymerase chain reaction; western blot; applied biochemistry; tillämpad biokemi; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : A low success rate of drug candidates in clinical trials, and especially in brain research, motivates development of better screening models. Hence, in neuroscience and many other fields of Life Science, development of more physiological relevant experimental cell-based models is motivated. LÄS MER