Sökning: "structure elucidation"

Hittade 4 uppsatser innehållade orden structure elucidation.

  1. 1. Study of fibrillation processes of amyloid-like β-lactoglobulin protein

    Master-uppsats, KTH/Kemi

    Författare :Jose Nixon; [2021]
    Nyckelord :bLG; Thioflavin-T Fluroscence; Fibrillation; bLG; Thioflavin-T fluroscens; fibrillering;

    Sammanfattning : Bovint β-laktoglobulinprotein (bLG) är ett litet globulärt protein med 162 aminosyrarester, som vanligtvis finns i mjölkvassle. Under sura förhällanden dissocierar dessa dimera proteiner och bildar amyloidliknande fibriller. LÄS MER

  3. 2. Elucidation of structural Properties of amyloid-like Fibrils via Solid State NMR

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Malisa Mantonico; [2018]
    Nyckelord :;

    Sammanfattning : The invention of plastic has revolutionized people's life style not only by facilitating the storage and transportation of various goods but also by improving mechanical properties of mankind's technological advances. However, plastic is considered to be harmful, as it contains toxic chemical compounds which are accumulated due to its persistence. LÄS MER

  4. 3. Photodegradation study of 3,5-diamino-6-chloro- N-(2-(methylamino)ethyl)pyrazine-2-carboxamide using preparative SFC and LC-MS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Sara Sillén; [2016]
    Nyckelord :photodegradation; UPLC; SFC; liquid chromatography; supercritical fluid chromatography; mass spectrometry; freeze drying; 18O-water; analytical chemistry; structure elucidation; photodegradants;

    Sammanfattning : In this project the photodegradation of 3,5-diamino-6-chloro-N-(2-(methylamino)ethyl)pyrazine-2-carboxamide was studied. A hypothetical degradation pattern for the compound was proposed and the aim of the project was to study the formed secondary photodegradants and to, if possible, structure elucidate some of these compounds. LÄS MER

  5. 4. Structural elucidation of mRNA(Sirt1)-microRNA 34a complex

    Master-uppsats, KTH/Skolan för teknikvetenskaplig kommunikation och lärande (ECE)

    Författare :Mona Farshchian; [2015]
    Nyckelord :mRNA Sirt1 ; miR-34a; in vitro transcription; gel electrophoresis; CD spectroscopy; NMR; cancer regulation via p53; HPLC; mRNA Sirt1 ; miR-34a; in vitro transkription; gel elektroforesis; CD spektroskopi; NMR; cancer regulering via p53; HPLC;

    Sammanfattning : The aim of this thesis is to understand RNA-RNA interactions steering cellular functions, as in the case of this thesis the structure of mRNA(Sirt1) in complex with microRNA-34a (miR-34a). MiR-34a regulates the cancer protein p53 via Sirt1 modulation. LÄS MER