Sökning: "vesicle"

Visar resultat 11 - 15 av 23 uppsatser innehållade ordet vesicle.

  1. 11. Synovial fluid components as synergistic lubricants in articular joint models

    Master-uppsats, KTH/Kemi

    Författare :Sixuan Li; [2019]
    Nyckelord :synergistic lubrication; synovial fluid; biolubrication; DPPC; hyaluronic acid; Mini-Traction Machine; macro- and microscale; profilometer;

    Sammanfattning : The excellent lubrication present within mammalian synovial joints attracted scientific interest, and some close-to-realistic models were applied to study the mechanism in vitro. In this project, the synergistic lubrication of synovial fluid was investigated by using 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC), hyaluronic acid (HA), and phosphate-buffered saline (PBS buffer) to mimic the synovial fluid. LÄS MER

  2. 12. Native incorporation of outer membrane proteins into vesicles suitable for high resolution NMR spectroscopy

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Mohammed Mouhib; [2018]
    Nyckelord :;

    Sammanfattning : Nuclear Magnetic Resonance spectroscopy is a powerful tool for studying the structure and dynamics of membrane proteins. The method has mainly been used for membrane proteins solubilized in detergent or embedded in membrane mimetic systems. LÄS MER

  3. 13. Constructing supported lipid bilayers from native cell membranes

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Tommy Dam; [2018]
    Nyckelord :T cells; Model membrane systems; Supported lipid bilayers; SLB; biophysical chemistry; biofysikalisk kemi; Chemistry;

    Sammanfattning : The aim of this MSc-project was to investigate whether it is possible to incorporate native cell membrane components from Jurkat T cells into supported lipid bilayers, SLBs, to produce a model membrane system better resembling the native cell membranes in T cells. The procedure of forming native-like SLBs (nSLB) was adapted from an existing protocol and is done through the deposition of hybrid vesicles onto a cleaned glass slide. LÄS MER

  4. 14. The effects of differentiationand neurotoxin on the global geneexpression in neuronal cells

    Uppsats för yrkesexamina på avancerad nivå,

    Författare :Robin Olofsson; [2017]
    Nyckelord :Neuroblastoma; Bioinformatics; Microarray data; BoNT A;

    Sammanfattning : Botulinum neurotoxin type A (BoNT/A) is a neurotoxin created by some strains of bacteria inthe family Clostridium. The toxin causes the disease Botulism that has symptoms of paralyzesthat can last for several weeks. Neuroblastoma cell lines were treated with the toxin BoNT/A.These kinds of cells are a common cancer form in children. LÄS MER

  5. 15. A calorimetric study of α-synuclein fibril formation & peptide induced vesicle leakage

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Emil Axell; [2017]
    Nyckelord :Differential Scanning Calorimetry; ITC; Isothermal Titration Calorimetry; Parkinson; α-synuclein; Alpha synuclein; DSC; Melittin; Vesicles; biochemistry; biokemi; Chemistry;

    Sammanfattning : The small protein α-synuclein is strongly associated with Parkinson’s disease. This protein is found in inclusion bodies, named lewy bodies inside neurons of people suffering from the disease. α-synuclein is very abundant in the human brain, and its normal function is still elusive and unclear. LÄS MER