Sökning: "Adverse Drug Reactions"

Visar resultat 1 - 5 av 38 uppsatser innehållade orden Adverse Drug Reactions.

  1. 1. Utilizing Transformers with Domain-Specific Pretraining and Active Learning to Enable Mining of Product Labels

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för beräkningsvetenskap

    Författare :Erik Norén; [2023]
    Nyckelord :Machine Learning; Natural Language Processing; NLP; BERT; Active Learning; AL; Pharmacovigilance; UMC; Uppsala Monitoring Centre; Structured Product Label; SPL; Transformers; Domain-Specific Pretraining; NER; Named Entity Recognition; Adverse Drug Reaction; ADR;

    Sammanfattning : Structured Product Labels (SPLs), the package inserts that accompany drugs governed by the Food and Drugs Administration (FDA), hold information about Adverse Drug Reactions (ADRs) that exists associated with drugs post-market. This information is valuable for actors working in the field of pharmacovigilance aiming to improve the safety of drugs. LÄS MER

  3. 2. Behov och intresse av digital biverkningsinformation hos allmänheten : En enkätstudie i Stockholms län

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Agnes Engström; [2021]
    Nyckelord :;

    Sammanfattning : Background  The implementation of patient centered care in the healthcare system has increased the involvement of patients in decisions regarding their own healthcare. Adverse drug reactions (ADR) information has been identified as the most requested health information by patients. LÄS MER

  4. 3. Creation of a Next-Generation Standardized Drug Groupingfor QT Prolonging Reactions using Machine Learning Techniques

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för systemteknik

    Författare :Jacob Tiensuu; Elsa Rådahl; [2021]
    Nyckelord :Pharmacovigilance; Adverse Drug Reactions; MedDRA; VigiBase; WHODrug Global; QT prolongation; Torsades de Pointes; Individual Case Safety Reports; Text Recognition; Standardised Drug Grouping; Multinomial Logistic Regression; BERT;

    Sammanfattning : This project aims to support pharmacovigilance, the science and activities relating to drug-safety and prevention of adverse drug reactions (ADRs). We focus on a specific ADR called QT prolongation, a serious reaction affecting the heartbeat. Our main goal is to group medicinal ingredients that might cause QT prolongation. LÄS MER

  5. 4. Service innovation in the pharmaceutical industry : How do existing value propositions restrict the adoption of new resources?

    Kandidat-uppsats, Uppsala universitet/Företagsekonomiska institutionen

    Författare :Johan Jansson; Anton Anhammer; [2021]
    Nyckelord :Service-dominant logic; service innovation; value proposition; practices; restrictions; digital resources; pharmaceutical industry.;

    Sammanfattning : The topics of value propositions and service innovation have been highly interesting topics within service-dominant logic. Something that has not been studied in previous research, and the purpose of this thesis, is to investigate; how current value propositions restrict service innovation by restricting digital resource utilization. LÄS MER

  7. 5. Using Machine Learning to Understand Text for Pharmacovigilance: A Systematic Review

    Master-uppsats, Luleå tekniska universitet/Institutionen för system- och rymdteknik

    Författare :Patrick Pilipiec; [2021]
    Nyckelord :;

    Sammanfattning : Background: Pharmacovigilance is a science that involves the ongoing monitoring of adverse drug reactions of existing medicines. Its primary purpose is to sustain and improve public health. LÄS MER