Sökning: "Bioinformatic tools"
Visar resultat 1 - 5 av 15 uppsatser innehållade orden Bioinformatic tools.
1. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes
Master-uppsats, Lunds universitet/Examensarbeten i bioinformatikSammanfattning : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. LÄS MER
2. Developing a reproducible bioinformatics workflow for canine inherited retinal disease
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Inherited Retinal Degenerations (IRDs) are a heterogenous group of diseases which lead to vision impairment and can be found both in humans and in dogs. About 1 in 1,380 humans is estimated to suffer from an autosomal recessive IRD, which would be 5.5 million people worldwide, and many more are estimated to be unaffected carriers. LÄS MER
3. Computational detection of human papilloma virus in the cervical cancer genome
Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Global research and development have witnessed new horizons in technological advancements, especially in the use of new-generation bioinformatic tools to solve human needs. Cervical cancer, caused by a sexually transmitted virus like human papillomavirus (HPV), is one of the most common cancers threatening women's health. LÄS MER
4. Immunological Cross-Reactivity : Construction of a Workflow That Enables Cross-Reactivity Predictions
Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Cross-reactivity occurs when an antibody binds to the epitope of a protein that is not the targeted antigen. This is problematic in the analysis of immunoassay diagnostics. Detecting a protein incorrectly might cause issues such as incorrect mapping of metabolic conditions for research or diagnosis. LÄS MER
5. Characterisation of structure and stability differences between the C-lobes of human and P. falciparum calmodulin in the presence of calmidazolium
Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologiSammanfattning : Malaria is a serious disease that can lead to fatal consequences if not treated. It is mainly spread via Plasmodium falciparum, a parasite carried by mosquitoes as host organisms. As a potential way of treating malaria, research is being done on possible inhibitors of calmodulin (CaM) in the parasite. LÄS MER