Sökning: "gene mutation"

Visar resultat 1 - 5 av 110 uppsatser innehållade orden gene mutation.

  1. 1. P-glykoprotein-mutationen - ABCB1-1Δ hos collies i Sverige

    Master-uppsats, SLU/Dept. of Anatomy, Physiology and Biochemistry

    Författare :Alice Gustafsson; [2024]
    Nyckelord :P-glykoprotein; ABCB1; ABCB1-1Δ; MDR1; collie;

    Sammanfattning : P-glykoprotein är ett effluxprotein som uttrycks på olika luminala ytor i flera organ, bland annat tarmväggen, njurtubuli, i leverns gallgångar samt i blodhjärnbarriären. Proteinet kodas av genen ABCB1 hos hund. LÄS MER

  3. 2. Analysis of relatedness and genetic diversity in Swedish sheep breeds using medium density (50K) SNP data

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Krishani Devika Wijesinghe Sinhalage; [2023]
    Nyckelord :sheep; genetic diversity; population structure; inbreeding; runs of homozygosity; coat colour; MC1R;

    Sammanfattning : The local Swedish sheep breeds belong to a group of sheep breeds known as North European short-tailed sheep breeds. Evaluation of genetic diversity, relatedness, and population structure of local breeds offers crucial metrics to prevent inbreeding depression, genetic erosion, and crossbreeding between locally adapted and exotic sheep breeds since these occurrences can have detrimental effects and ultimately lead to extinction. LÄS MER

  4. 3. Expression of complement factor C1r and C1s in human gingival fibroblasts

    Master-uppsats, Umeå universitet/Institutionen för odontologi

    Författare :Hanna From; [2023]
    Nyckelord :fibroblasts; pEDS; C1r; C1s;

    Sammanfattning : Background: Periodontitis is an inflammatory condition rendering in degradation of tooth supporting tissue. In the inflammatory process cytokines, amongst others TNF-a, IL-1b and IL-6 play an important role in regulating the immune response. LÄS MER

  5. 4. Method development of magnetic cell isolation and DNA extraction of small cell populations from Ficoll-separated hematopoietic cells

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Dominika Debowska; [2023]
    Nyckelord :Clonal haematopoiesis of indeterminate potential CHIP ; hematopoietic stem cell; automated cell separation; silica-membrane-based nucleic acid purification.;

    Sammanfattning : Clonal haematopoiesis of indeterminate potential, or CHIP are a family of mutations present in the general population. CHIP-mutations are prevalent in the haematopoietic stem cells and in the more mature cell populations, T-lymphocytes, B-lymphocytes and myeloid cells (CD3+, CD19+ and CD33+ cells) in blood. LÄS MER

  7. 5. An Overview Of The Antibiotic Resistance Mechanisms Of Common Gram Positive And Gram Negative Multidrug Resistant Bacteria

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för biologi och miljö (BOM)

    Författare :Elisabeth Tammi; [2023]
    Nyckelord :Antibiotic resistance mechanism; gram negative bacteria; gram positive bacteria;

    Sammanfattning : Antibiotic resistance in multidrug resistant bacteria cause high mortality rates worldwide, where there has been over 1,000,000 deaths reported as of the year 2019. Antibiotics were thought to be the cure for fighting infectious diseases and preventing further spreading of infection. LÄS MER