Sökning: "ligand"

Visar resultat 11 - 15 av 148 uppsatser innehållade ordet ligand.

  1. 11. Antikroppssvar och PD-1/PD-L1 nivåer efter Covidvaccination

    Kandidat-uppsats, Karlstads universitet

    Författare :Elin Lindgren; [2023]
    Nyckelord :Antibody Response; Covid-19; pd1; pdl1; pd-1; pd-l1; immune system; immune response; vaccination; vaccine; corona; Sars-CoV-2; immune inhibitors; antikroppssvar; covid-19; pd1; pdl1; pd-1; pd-l1; immunförsvar; vaccination; vaccin; corona; sars-cov-2; immuninhibitorer;

    Sammanfattning : The virus SARS-CoV-2 gave rise to a global pandemic and several vaccines, whose efficiency needed to be evaluated, have been developed. Our immune system is regulated by several mechanisms that activate and inhibit immune response. LÄS MER

  3. 12. Approaches to Structural Characterization of a Heteromeric GABA(A)R

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Alexander Stevens; [2023]
    Nyckelord :Applied Physics; Biophysics; Molecular Biophysics; GABA A R; LGIC; pLGIC; Tillämpad Fysik; Biofysik; Molekylär Biofysik; GABA A R; LGIC; pLGIC;

    Sammanfattning : Structural biology has become an important part of researching various diseases and drug development. In this thesis, I provide details on how I worked with approaches to structural characterization of a heteromeric GABA(A)R. LÄS MER

  4. 13. Development of a cell killing adenovirus with a novel cytotoxic transgene

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Carl Blomqvist; [2023]
    Nyckelord :;

    Sammanfattning : Cancer is among the most common causes of human deaths globally. Because of limitations and adverse effects of conventional cancer treatments, the need for new treatments is imminent. LÄS MER

  5. 14. Understanding the Activation Mechanism of the D2 Dopamine Receptor Modulated by Dopamine and Adrenaline via Machine Learning

    Kandidat-uppsats, KTH/Skolan för teknikvetenskap (SCI)

    Författare :Astrid Frykman; Sophia Bröte; [2023]
    Nyckelord :;

    Sammanfattning : The dopamine receptor is one of the main therapeutic targets for neurological disorders, such as Parkinson’s disease and schizophrenia. Although dopamine and adrenaline are structurally similar and both bind to the D2 dopamine receptor, they activate the receptor differently. LÄS MER

  7. 15. Jämförelse av aktivitet i urinblåsan hos 18F-PSMA-PET patienter med och utan hydrering

    Kandidat-uppsats, Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Författare :Salma Elsaid; [2023]
    Nyckelord :Activity in urinary bladder; 18F-PSMA-PET; hydration; PET-CT prostate cancer.;

    Sammanfattning : Background: Prostate cancer is the most prevalent form of cancer affecting men.In case of biochemical recurrence, positron emission tomography (PET) targeting prostate-specific membrane antigen (PSMA) on prostate tumor cells is primarily used, in combination with computed tomography (CT), for detection and localization of recurrence. LÄS MER