Sökning: "Biofysik"

Visar resultat 1 - 5 av 10 uppsatser innehållade ordet Biofysik.

  1. 1. Approaches to Structural Characterization of a Heteromeric GABA(A)R

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Alexander Stevens; [2023]
    Nyckelord :Applied Physics; Biophysics; Molecular Biophysics; GABA A R; LGIC; pLGIC; Tillämpad Fysik; Biofysik; Molekylär Biofysik; GABA A R; LGIC; pLGIC;

    Sammanfattning : Structural biology has become an important part of researching various diseases and drug development. In this thesis, I provide details on how I worked with approaches to structural characterization of a heteromeric GABA(A)R. LÄS MER

  3. 2. The role of gap junctions in coordination of intercellular Ca2+ signaling

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Emma Latron; [2023]
    Nyckelord :applied physics; biophysics; Calcium; MDCKII; Gap Junctions; signalling; Segmentation; Tillämpad fysik; Biofysik; Kalcium; MDCKII; Gap Junctions; signalering; segmentering;

    Sammanfattning : Calcium ions are one of the most versatile signalling molecules. They are essential tothe proper functioning of various cellular processes in many different types of cells.The calcium signals have been studied in the past using ratiometric dyes like Fura-2. LÄS MER

  4. 3. Characterization of Alcohol Modulation of a Pentameric Ligand-gated Ion Channel with Electrophysiology and Molecular Dynamics Simulations

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Sabina Gutheim; [2021]
    Nyckelord :Biophysics; Electrophysiology; MD simulations; Ligand-gated ion channels; GLIC; Ethanol modulation; Biofysik; Elektrofysiologi; MDsimuleringar; Pentameriska ligandstyrda jonkanaler; GLIC; Etanolmodulering;

    Sammanfattning : Pentameric ligand-gated ion channels (pLGICs) are membrane receptors that play a crucial role in every living organism. The pLGIC protein structure forms a pore through the membrane of a cell that can let specific ions pass through, upon activation by endogenous agonists. LÄS MER

  5. 4. The sensitivity of the EMC algorithm to the light intensity and amount of diffraction patterns in diffraction experiments

    Kandidat-uppsats, Uppsala universitet/Institutionen för fysik och astronomi; Uppsala universitet/Molekylär biofysik

    Författare :Johanna Rogvall; [2021]
    Nyckelord :Diffraction; EMC; coherent diffraction imaging; Condor; XFEL;

    Sammanfattning : To understand the function of macromolecules like proteins it helps to know the structure of the molecule. Coherent diffraction imaging is an emerging method that might be used to figure out the structures of macromolecules. LÄS MER

  7. 5. Improving the temporal resolution of a microspectrometer for the study of the photophysics of enhanced green fluorescent protein

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Lukas Rane; [2021]
    Nyckelord :Biophysics; EGFP; Fluorescence; triplet state; Biofysik; EGFP; fluorescens; triplet tillstånd;

    Sammanfattning : The use of fluorescent proteins as fluorescent markers has exploded over the last decades. In particular due to the development of advanced microscopy for live cell measurements, dynamic molecular studies down to single molecule levels and for superresolution microscopy. LÄS MER