Sökning: "mabselect"

Hittade 3 uppsatser innehållade ordet mabselect.

  1. 1. Modeling & Simulation of Affinity Chromatography & Investigation of CaptureSMB

    Master-uppsats, Lunds universitet/Kemiteknik (CI)

    Författare :Dennis Bogren; [2018]
    Nyckelord :Affinity chromatography; simulation of chromatography; breakthrough curve; CaptureSMB; chemical engineering; kemiteknik; Technology and Engineering;

    Sammanfattning : Chromatography was first described in the 1903 by a Russian scientist. Later on chromatography was almost forgotten until the 1940s when two British scientist published a study about liquid chromatography. They were later awarded with the Nobel prize in chemistry for their work in chromatography. LÄS MER

  3. 2. Development of Cleaning-in-Place Procedures for Protein A Chromatography Resins using Design of Experiments and High Throughput Screening Technologies

    Uppsats för yrkesexamina på grundnivå, Institutionen för fysik, kemi och biologi

    Författare :Hanna Tengliden; [2008]
    Nyckelord :Cleaning-in-Place; Protein A chromatography; Design of Experiments; High Throughput; MabSelect; ;

    Sammanfattning : Robust and efficient cleaning procedures for protein A chromatography resins used for production of monoclonal antibody based biopharmaceuticals are crucial for safe and cost efficient processes. In this master thesis the effect of different cleaning regimes with respect to ligand stability of two protein A derived media, MabSelectTM and MabSelect SuReTM, has been investigated. LÄS MER

  4. 3. Affinity Determination of Protein A Domains to IgG subclasses by Surface Plasmon Resonance

    Magister-uppsats, Institutionen för fysik, kemi och biologi

    Författare :Sofia Nohldén; [2008]
    Nyckelord :Protein A; antibodies; IgG; SPR; Biacore; affinity determination;

    Sammanfattning : A capture step with protein A is the most common purification step in the downstream purification process of monoclonal antibodies. It is therefore of great importance to increase the knowledge of the interactions involved in this purification technique. LÄS MER