Sökning: "polygenic risk"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden polygenic risk.

  1. 1. Dyslexia, ADHD and Educational Attainment using Polygenic Score: A Meta-analysis

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Simon Lindhagen; [2023]
    Nyckelord :developmental dyslexia; attention deficit hyperactivity disorder; educational attainment; polygenic score; meta-analysis;

    Sammanfattning : Developmental Dyslexia (DD), Attention Deficit Hyperactivity Disorder (ADHD), and Educational Attainment (EA) are highly prevalent conditions that have a significant impacton individuals' academic and social functioning. These conditions have a complex genetic basis and are often comorbid. LÄS MER

  3. 2. Influences of genetically predicted and attained education on geographical mobility and their association with mortality : A cohort study investigating the influence of genetic predisposition to higher education as well as attained education on geographic mobility and differences in mortality risk in Swedish twins born 1926-1955

    Master-uppsats, Stockholms universitet/Institutionen för folkhälsovetenskap

    Författare :Elsa Ojalehto; [2022]
    Nyckelord :Polygenic score; Attained education; Geographic mobility; Mortality; Socioeconomic status;

    Sammanfattning : Introduction Research show that both educational attainment and genetic propensity to education (PGSEdu) can be associated with geographic mobility and that individuals living in more deprived areas tend to have poorer health while those living in more advantaged places tend to have better health. In this thesis, the aim was to study how polygenic scores for education and attained education influence and differ by geographic mobility, and how they influence the association between geographic mobility and mortality. LÄS MER

  4. 3. Polygenic risk for schizophrenia and non-pathological cognitive aging

    Master-uppsats, Umeå universitet/Institutionen för psykologi

    Författare :Nasimeh Naseri; [2020]
    Nyckelord :Schizophrenia; polygenic risk; ageing; cognition; Schizofreni; poly-genetisk risk; åldrande; kognition;

    Sammanfattning : Schizophrenia is a severe psychiatric disorder associated with cognitive impairments. Polygenic risk for schizophrenia (SCZ-PGR) has been associated with poor performance in cognitive tasks, both in patients and in healthy individuals. It has also been suggested that schizophrenia is associated with accelerated aging. LÄS MER

  5. 4. Etiology of patellar luxation in small breed dogs

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Ana-Marija Camber; [2017]
    Nyckelord :patellar luxation; canine; dog; loose patella;

    Sammanfattning : Patellaluxation (PL) är en vanlig ortopedisk sjukdom som karakteriseras av att patellan kan luxera från trochlea ossis femoris. Detta sker antingen manuellt, spontant när hunden är i rörelse eller så är patellan permanent fixerad utanför fåran. LÄS MER

  7. 5. Karakterisering av genetiska riskfaktorer för dilaterad kardiomyopati hos hund

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Sofia Jankulovska; [2017]
    Nyckelord :dilaterad kardiomyopati; hund; grand danois; newfoundlandshundar; genetisk associationsstudie; next-generation sequencing; digitalPCR; genetiska riskfaktorer; dilated cardiomyopathy; canine; grand danois; Newfoundlands dogs; genome-wide association studies; next-generation sequencing; digitalPCR; genetic risk factors;

    Sammanfattning : Dilaterad kardiomyopati (DCM), är en hjärtsjukdom som förekommer hos ett flertal hundraser. Etiologin är inte fastställd. Genetiska studier på hund visar att gener involverade i utvecklandet av DCM skiljer sig åt mellan olika hundraser. LÄS MER