Sökning: "sandwich assay"

Visar resultat 1 - 5 av 7 uppsatser innehållade orden sandwich assay.

  1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Sam Vadi Dris; [2024]
    Nyckelord :Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

    Sammanfattning : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. LÄS MER

  3. 2. The GSK-3 inhibitor has no effect on production of IL-1β in LPS- and Nigericin-stimulated THP-1 macrophages

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Jessica Halan Söderberg; [2022]
    Nyckelord :;

    Sammanfattning : Inflammation is the body's natural defense reaction and is known since ancient times. The inflammation is divided into two main phases, acute and chronic inflammation dependent on the process and cellular mechanisms of the inflammation. LÄS MER

  4. 3. Effectivization of GAD ELISA : Method-transfer from Dynex DSX to Tecan Freedom EVOlyzer

    Kandidat-uppsats, Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Författare :Juan Manuel Bernal Salazar; [2022]
    Nyckelord :Effectivization; Antibodies; ELISA; GAD; GAD65; Method transfer; Type 1 Diabetes Mellitus;

    Sammanfattning : Due to a growing demand and need for faster results, effectivization as a concept has been pushed to the forefront of medical research. Here, a method transfer between 2 fully automized ELISA instruments is highlighted. The instruments were the Tecan Freedom EVOlyzer and the Dynex DSX. LÄS MER

  5. 4. Activation of NLRP3 inflammasome leads to the differential secretion of interleukins 1*/18 possibly linked to pyroptosis in THP-1 cells

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Jana Damiani; [2020]
    Nyckelord :;

    Sammanfattning : Organisms are constantly exposed to microorganisms, some of which can cause disease, and yet, sickness only rarely occurs. Upon infection, the immune system is mobilized to eliminate the threat and re-establish homeostasis. LÄS MER

  7. 5. Development of Sandwich Assays for Potential Protein Biomarkers in Neurodegenerative Diseases

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Jamil Yousef; [2020]
    Nyckelord :Biomarkers; cerebrospinal fluid; neurodegenerative diseases; neuroproteomics; sandwich assay; suspension bead array.; Biomarkörer; ryggmärgsvätska; neurodegenerativa sjukdomar; neuroproteomik; sandwich assay; suspension bead array.;

    Sammanfattning : As the aging population is increasing worldwide, so is the prevalence of neurodegenerativediseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal dementia(FTD) and amyotrophic lateral sclerosis (ALS). Reliable biomarkers able to aid the diagnosis anddifferentiation of these diseases are needed in order to start the right treatment as early as possible. LÄS MER