Sökning: "surface proteins"

Visar resultat 21 - 25 av 130 uppsatser innehållade orden surface proteins.

  1. 21. Inhibited surface-thiols in Geobacter sulfurreducens : Mercury uptake and methylation rates

    Master-uppsats, Umeå universitet/Kemiska institutionen

    Författare :Andreas Granström; [2021]
    Nyckelord :;

    Sammanfattning : Due to daily human (anthropogenic) industrial activity, a lot of elemental mercury (Hg0) has been released to the atmosphere. The mercury can then spread globally, since mercury has the ability to remain atmospheric for up to a year. When mercury deposits, it can end up in anaerobic environments such as sediments and soil. LÄS MER

  2. 22. UTVÄRDERING AV FLUORESCERANDE PROTEINER I DET RÖDA SPEKTRUMET SOM MARKÖRER I GENETISKA KRETSAR SKAPADE FÖR IMMUNTERAPI AV CANCER

    Kandidat-uppsats, Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Författare :Caroline Persson; [2021]
    Nyckelord :BFP; CAR T-celler; Fluorescerande protein; genetisk krets; GFP; immunterapi; plasmid; Lentivirus;

    Sammanfattning : Fluorescerande protein kan användas som reportrar i genetiska kretsar för att identifiera framgångsrikt modifierade celler. Med hjälp av syntetisk biologi kan genetiska kretsar, som är en sammansättning gener som kodar för protein, skapas. LÄS MER

  3. 23. Formulation development of a recombinant VAR2-antiCD3 protein for cancer immunotherapy

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Maja Warlin; Frida Hallberg; [2021]
    Nyckelord :immunotherapy; cancer; pharmaceuticals; proteins; analytical techniques; molecular biotechnology; formulation; life science; engineering; pharmaceutical technology; Technology and Engineering;

    Sammanfattning : The use of immunotherapy for treating cancer has received a lot of attention in the recent years. The therapy is based on activating or deactivating the patient’s own immune system to help fight the disease. One way of doing this, is using bispecific molecules that can target both cancer cells and T-cells simultaneously. LÄS MER

  4. 24. Development of an Affibody-based Prodrug Against HER2 for Cancer Therapy

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Cornelia Westerberg; [2021]
    Nyckelord :Affibody; therapeutic protein; prodrug; affibody-based prodrug; HER2-targeted therapy;

    Sammanfattning : Affinity proteins constitute an important category of cancer therapeutics. Owing to properties such as high target affinity and selectivity, therapeutic proteins offer more targeted therapy than small molecule drugs. The target molecules are typically proteins that are overexpressed on the surface of tumour cells, such as membrane-bound receptors. LÄS MER

  5. 25. Affinity Based Capture of Circulating Tumour Cells Using Designed Ankyrin Repeat Proteins (DARPins) in a Microfluidic System

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Emil Spåre; [2021]
    Nyckelord :Designed ankyrin repeat proteins; DARPins; microfluidics; circulating tumour cells; affinity based cell capture; surface modification; Designade ankyrinupprepningsproteiner; DARPiner; mikrofluidik; cirkulerande tumörceller; affinitetsbaserad celluppfångst; ytförändring;

    Sammanfattning : Designade ankyrinupprepningsproteiner (DARPiner) är små, mycket stabila antikroppsmimetiska proteiner. I det här projektet användes anti-EpCAM-DARPiner tillsammans med mikrofluidik för att avgära om de kunde fånga upp HCT116-celler mer effektivt än anti-EpCAM-antikroppar. LÄS MER