Sökning: "tumour"

Visar resultat 16 - 20 av 242 uppsatser innehållade ordet tumour.

  1. 16. The role of AmotL2 in the regulation of mesenchymal transitioning of endothelial cells

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Anita-Ann Monteiro; [2023]
    Nyckelord :Endothelial-mesenchymal transition EndMT ; atherosclerosis; transforming growth factor β TGF-β ; Angiomotin-Like 2 AmotL2 ; Scrambled Scr ; knockdown kd ; Immunofluorescence IF ;

    Sammanfattning : Background During development, endothelial cells acquire mesenchymal-like properties to migrate and facilitate normal vascular formation. This process of transformation is known as endothelial to mesenchymal transition (EndMT) and has also been implicated in diseases like vascular pathologies contributing to endothelial inflammation, atherosclerosis and tumour angiogenesis. LÄS MER

  3. 17. Omvårdnad vid hjärntumör : Utifrån sjuksköterske- och patientperspektivet

    Kandidat-uppsats, Högskolan i Halmstad/Akademin för hälsa och välfärd

    Författare :Tella Ingvarsson; Matilda Karlsson; [2023]
    Nyckelord :Brain neoplasm; nursing; nurse; patient; Hjärntumör; omvårdnad; sjuksköterska; patient;

    Sammanfattning : Bakgrund: Maligna hjärntumörer är aggressiva, med diverse omfattande symtom som beror på graden av malignitet samt tumörens placering. Patienter med malign hjärntumör upplever ofta kognitiva symtom, vilket hotar patientens autonomi och delaktighet i vården. Sjuksköterskor upplever ofta en rädsla kring att möta patientens behov. LÄS MER

  4. 18. Molecular mapping of the HGSOC tumour microenvironment

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Philippine Louail; [2023]
    Nyckelord :Immunology; Ovarian cancer; Multiplex Immunofluorescence; scRNA sequencing; Bioinformatics; Image analysis;

    Sammanfattning : High-grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer, and its heterogeneity poses a challenge for the discovery of reliable diagnostic biomarkers, therapeutic targets, and predicting treatment response, particularly to immunotherapy. The current standard diagnostic and treatment options are inadequate, resulting in late diagnosis and poor prognosis. LÄS MER

  5. 19. Patienters upplevelser av att leva med stomi : En litteraturstudie

    Kandidat-uppsats, Röda Korsets Högskola

    Författare :Maja Engman; Veronika Ferreira Pinho; [2023]
    Nyckelord :care; experience; nursing; stoma;

    Sammanfattning : Background: An ostomy is an artificial opening in the abdomen of a person as a response to a bowel disease, tumour or other issues affecting the bowels. Approximately 43 000 people live with a stoma in Sweden presently. Patients need to be offered information, education and psychological support linked to the stoma procedure. LÄS MER

  7. 20. CYP2D6 loss of heterozygosity - a potential target for neuroblastoma therapy

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Jordan Dupuis; [2023]
    Nyckelord :Loss of Heterozygosity; CYP2D6; Neuroblastoma; Collateral Lethality; Precision Cancer Medicine;

    Sammanfattning : Loss of heterozygosity events, whereby alleles are lost at heterozygous chromosomal loci, are associated with cancer formation and may result in the deletion of numerous genes encoding enzymes that have critical activities within the cell. Consequently, vulnerabilities are created that are absent in normal cells which can be targeted using a precision medicine approach called collateral lethality. LÄS MER