Sökning: "Affinity"

Visar resultat 11 - 15 av 465 uppsatser innehållade ordet Affinity.

  1. 11. Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Theranostics

    Författare :Astrid Haraldsson; [2023]
    Nyckelord :PNA; pretargeting; cancer therapy; cytotoxic payload;

    Sammanfattning : One of the major challenges in cancer treatment is delivering high enough doses of active substance specifically to cancer cells without accumulation in healthy organs. Pretargeting has emerged as a potential solution, where the delivery of a cancer recognizing (primary) agent and a cancer killing (secondary) agent are separated. LÄS MER

  3. 12. Detecting Chromatography Unit Degradation : Comparison of single- and multi-point techniques implemented in system control and monitoring software

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Signaler och system

    Författare :Max Markensten; [2023]
    Nyckelord :PCA; SOP-MPT; Fibro; chromatography; affinity A;

    Sammanfattning : Chromatography units, used in the production of pharmaceuticals, degrade with use and need to be changed or repackaged. This study investigates the effectiveness of two statistical methods, principal component analysis and simple and one-point multiparameter technique, for determining degradation in the Fibro chromatography unit. LÄS MER

  4. 13. Investigation of enzymatic mediated CO2 capture : A computational study of enzymatic systems

    Kandidat-uppsats, Karlstads universitet/Institutionen för ingenjörs- och kemivetenskaper (from 2013)

    Författare :Amelie Grunditz; [2023]
    Nyckelord :;

    Sammanfattning : Enzymes converting CO2 can be helpful with battling today’s environmental problems with global warming due to greenhouse gases. It can also contribute to make industrial processes cheaper and cleaner. During this project, enzymes have been studied to understand the process better. LÄS MER

  5. 14. Upplevelser av djurassisterad terapi hos personer med psykisk ohälsa : en litteraturöversikt

    Kandidat-uppsats, Sophiahemmet Högskola

    Författare :Nicole Sköld Herrera; Victoria Norell; [2023]
    Nyckelord :Animal-assisted therapy; Experiences; Mental health; Nursing care; Djurassisterad terapi; Omvårdnad; Psykisk ohälsa; Upplevelser;

    Sammanfattning : Bakgrund Djur tjänar som lojala och betydelsefulla följeslagare, som förser oss med villkorslös kärlek, tillgivenhet, och kamratskap. Varje människa är unik och ska bemötas efter sina förutsättningar. LÄS MER

  7. 15. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Beräkningsbiologi och bioinformatik

    Författare :Linde Brokmar; [2023]
    Nyckelord :Protein design; de novo design; protein engineering; generative ai; machine learning; peptide binders; AF2; EvoBind; RFdiffusion; ProteinMPNN;

    Sammanfattning : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. LÄS MER