Sökning: "genotype"

Visar resultat 1 - 5 av 124 uppsatser innehållade ordet genotype.

  1. 1. Development of a novel quantitative PCR analysis method for HIV-1

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Teoretisk kemi

    Författare :Anna-Malin Hallberg; [2021]
    Nyckelord :HIV; PCR; primers; probes; virus; detection; blood plasma; pathogen; biological pharmaceutical; protein-based pharmaceutical; genotype; subtype; RT qPCR; extraction; TaqMa; RNA virus; cross-dimer; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Sammanfattning : Biological pharmaceuticals are the answer to many severe diseases of today’s society. Some of these are protein-based drugs and can be produced from human blood plasma. In order to guarantee the safety of patients, absence of any pathogens needs to be ensured. LÄS MER

  2. 2. Analysis of a Filifactor Alocis genotype and its effect on pathological progress in periodontitis

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Tandläkarutbildning; Umeå universitet/Tandläkarutbildning

    Författare :Jessica Radu; Kati Heinämäki; [2021]
    Nyckelord :;

    Sammanfattning : Background: Filifactor alocis is a gram positive, obligate anaerobic rod bacterium that has shown correlation to pathogenic events that may be linked to periodontitis. Previous studies have proved the presence of so-called “rtx” toxins in F. alocis that are similar to the leukotoxin of A. actinomycetemcomitans. LÄS MER

  3. 3. Neural networks for imputation of missing genotype data : An alternative to the classical statistical methods in bioinformatics

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Alfred Andersson; [2020]
    Nyckelord :genetics; imputation; bioinformatics; neural networks; GWAS;

    Sammanfattning : In this project, two different machine learning models were tested in an attempt at imputing missing genotype data from patients on two different panels. As the integrity of the patients had to be protected, initial training was done on data simulated from the 1000 Genomes Project. LÄS MER

  4. 4. Association of sickle cell disease with nutritional status among under-five children: a secondary analysis of Nigeria demographic and health survey 2018 data.

    Master-uppsats, Uppsala universitet/Internationell mödra- och barnhälsovård (IMCH)

    Författare :Ayeda Ahmed; [2020]
    Nyckelord :Ambreen;

    Sammanfattning : Abstract Background Malnutrition in childhood brings lots of difficulties that hinder to lead a healthy life. Nigeria is one of the most populous country in Africa has record of largest number of children suffered from chronic malnutrition under five years age. LÄS MER

  5. 5. Development and validation of a novel quantitative PCR analysis method for HIV-1

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Teoretisk kemi

    Författare :Josefine Sundgren; [2020]
    Nyckelord :HIV-1; qPCR; Octapharma; Taqman; applied biochemistry; tillämpad biokemi; Technology and Engineering;

    Sammanfattning : The major problem when developing primers and probe sets for detection of HIV-1 is its high genetic variability and strong ability to mutate. HIV-1 is divided into four groups, M, N, O, P based on genetic similarities, and there are more than 70 different circulating recombinant forms. LÄS MER