Sökning: "protein dimers"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden protein dimers.

  1. 1. Modelling Large Protein Complexes

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Ho Yeung Chim; [2023]
    Nyckelord :Protein Modeling; Monte Carlo Tree Search; Protein Complex;

    Sammanfattning : AlphaFold [Jumper et al., 2021, Evans et al., 2022] is a deep learning-based method that can accurately predict the structure of single- and multiple-chain proteins. However, its accuracy decreases with an increasing number of chains, and GPU memory limits the size of protein complexes that can be predicted. LÄS MER

  3. 2. Investigation of the function of the SH3-like domain of the Saccharopolyspora erythraea iron-dependent regulator

    Master-uppsats, Uppsala universitet/Institutionen för kemi - BMC

    Författare :Carita Hammar; [2022]
    Nyckelord :;

    Sammanfattning : The bacterium Saccharopolyspora erythraea is utilized to produce the widely used antibiotic erythromycin. With the increasing problem of antibiotic resistance, the development of derivatives of the drug is of great importance. To produce antibiotics biosynthetically, it is crucial to understand the metabolic pathways utilized by the bacterium. LÄS MER

  4. 3. Structure-based design of novel pharmacological tools for the A3 adenosine G protein-coupled receptor

    Master-uppsats, Uppsala universitet/Institutionen för läkemedelskemi

    Författare :Ashish Tamhankar; [2021]
    Nyckelord :;

    Sammanfattning : Adenosine receptors (ARs) are a family belonging to the GPCR superfamily, involved with multiple physiological processes and widely distributed throughout the body. In this study, we focus on the A3 AR due to its vast scale applications in various pathophysiological conditions such as inflammation, pain, allergic asthma, and cancer chemotherapy. LÄS MER

  5. 4. PREPARATION AND CHARACTERIZATION OF BOVINE MEAT AND MILK FACTOR VESICLES/PARTICLES & IDENTIFICATION OF MSBI1 REP INTERACTING PROTEINS

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Farhana Manzoor; [2020]
    Nyckelord :Bovine meat and milk factors; multiple sclerosis; immunoprecipitation co-immunoprecipitation; protein dimers; mass spectrometry; immunodetection; cesium chloride density gradient centrifugation; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; vesicle; particle; interaction partner; pull-down assay.;

    Sammanfattning : Introduction: Bovine meat and milk factors (BMMF) frequently isolated from bovine meat and milk, are discussed as putative causative agents for breast, colon and possibly other cancers. The hypothesis was formulated based on earlier correlative studies indicating that BMMFs could indirectly trigger inflammation, accumulate mutational events via reactive oxygen and nitrogen species production which eventually provokes tumor formation. LÄS MER

  7. 5. Recombinant expression of the cowpea chlorotic mottle virus

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Amanda Willas; [2019]
    Nyckelord :Biokemi; Biochemistry; Viruskapsid; Viruscaspid; CCMV; Chemistry;

    Sammanfattning : All viruses are composed of both genetic material and a capsid. The capsid is composed by identical protein subunits and the purpose is protection of the genetic material, in this case RNA. LÄS MER