Sökning: "Protein Modeling"

Visar resultat 1 - 5 av 27 uppsatser innehållade orden Protein Modeling.

  1. 1. The production of recombinant 6LZE_A and NS2B-NS3 in E. coli

    Master-uppsats, Lunds universitet/Bioteknik (master); Lunds universitet/Bioteknik (CI)

    Författare :Raluca Svensson; [2024]
    Nyckelord :coronavirus; dengue; protease; pandemic; SARS-Cov-2; DENV; viral replication; proteins; Escherichia coli; DL-BAPNA; computational modeling; recombinant protein production; biotechnology; Biology and Life Sciences;

    Sammanfattning : Even though the first coronavirus pandemic was registered in 1965, SARS-CoV-2 was better acknowledged when it caused the worldwide pandemic in 2019 in which millions of individuals lost their lives. Due to its facile way of spreading from one individual to another, the number of infected cases has gone up to more than 750 million to this day. LÄS MER

  3. 2. The Effect of Interactive Selection on Personalized Drug Prediction Using Interactomes : Examination of Parameters Impacting Drug Treatment Rankings from Network Models for Covid-19 Patients

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Cornelia Torell; [2023]
    Nyckelord :Precision Medicine; Pharmacogenomics; Biomarkers; Covid-19; Digital Twins; Network Modeling; Interactomes; Protein-Protein Interaction Networks; Differentially Expressed Genes; Principal Coordinate Analysis; Precisionsmedicin; Farmakogenetik; Biomarkörer; Covid-19; Digitala tvillingar; Nätverksmodellering; Interaktom; Proteininteraktionsnätverk; Sjukdomsrelaterade gener; Principalkoordinatanalys;

    Sammanfattning : Patients not responding to therapy as expected is one of the most pressing healthcare concerns of today. It causes economical, medical and societal issues along with suffering for patients. This project aimed to address this problem and evaluate how to find the best suited drug treatments for individual patients to treat Covid-19. LÄS MER

  4. 3. Suspensions of Calcium Phosphate : Interactions of milk proteins to hydroxyapatite

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Ying Chen; [2023]
    Nyckelord :Calcium fortification; Milk proteins interactions; Colloid chemistry; Food technology; engineering and nutrition; Agriculture and Food Sciences;

    Sammanfattning : Capolac is a product containing hydroxyapatite (HA) from Arla Food Ingredients, to be used for calcium fortification. The adsorption of casein and whey proteins onto the Capolac was investigated, aiming to solve the sedimentation problem of this insoluble calcium phosphate. LÄS MER

  5. 4. Modelling Large Protein Complexes

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Ho Yeung Chim; [2023]
    Nyckelord :Protein Modeling; Monte Carlo Tree Search; Protein Complex;

    Sammanfattning : AlphaFold [Jumper et al., 2021, Evans et al., 2022] is a deep learning-based method that can accurately predict the structure of single- and multiple-chain proteins. However, its accuracy decreases with an increasing number of chains, and GPU memory limits the size of protein complexes that can be predicted. LÄS MER

  7. 5. BAYESIAN HIERARCHICAL LINEAR MODELS FOR DIFFERENTIAL PROTEIN EXPRESSION ANALYSIS

    Master-uppsats, Uppsala universitet/Statistiska institutionen

    Författare :Siri Voghera; [2023]
    Nyckelord :Bayesian hierarchical modeling; differential protein expression analysis; proteomics;

    Sammanfattning : It is evident that the study of proteins is crucial for a deeper understanding of how drug treatments affect the body. However, differential protein expression analysis, which can be described as the method of finding which proteins are affected by a treatment, faces some major challenges. LÄS MER