Sökning: "proteinkonformationer"

Hittade 2 uppsatser innehållade ordet proteinkonformationer.

  1. 1. Transient state UV spectroscopy of Tyrosine and Tyrosine-containing protein

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Hongjian Chen; [2023]
    Nyckelord :Tyrosine; Calmodulin; Autofluorescence; Transient-state monitoring; Electronic state transitions; Tyrosin; Calmodulin; Autofluorescens; Transient-tillståndsövervakning; Elektroniska tillståndsövergångar;

    Sammanfattning : The aromatic amino acids tryptophan, tyrosine, and phenylalanine have been extensively used for different label-free protein studies. These investigations extract information on protein conformations and interactions from the emitted fluorescence's intensity, wavelength, and/or polarization. LÄS MER

  2. 2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Samuel Eriksson Lidbrink; [2023]
    Nyckelord :AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Sammanfattning : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. LÄS MER