Sökning: "Differential expression analysis"

Visar resultat 1 - 5 av 34 uppsatser innehållade orden Differential expression analysis.

  1. 1. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

    Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

    Författare :Yi Su; [2023]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. LÄS MER

  3. 2. Quality Control and Differential Analysis Tools for Sequencing Data with User-Friendly GUI Implementation Based on PySimpleGUI

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Mohit Bachan Singh Panwar; [2023]
    Nyckelord :;

    Sammanfattning : The paper details the development, implementation and assessment of a suite of bioinformatics tools, namely Adapter Trimmer, Quality Trimmer, Quality Filter  and two Differential Expression Analysis (DEA) tools based on existing libraries like edgeR via rpy2 and PyDESeq2. All these tools are unified within a consolodated graphical user interface (GUI), underscoring the focus on accessibility and user-centric design. LÄS MER

  4. 3. Profiling the Blood Proteome in Autoimmune Disease Using Proximity Extension Assay

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Julia Asp; [2023]
    Nyckelord :Plasma proteomics; proximity extension assay; autoimmune disease; differential expression; machine learning; biomarkers; Plasma proteomik; proximity extension assay; autoimmuna sjukdomar; differentiellt proteinuttryck; maskininlärning; biomarkörer;

    Sammanfattning : Autoimmuna sjukdomar är en samling komplexa, kroniska, inflammatoriska sjukdomstillstånd som kännetecknas av dysreglering av immunsystemet, vilket resulterar i inflammation och skada av vävnader, celler och organ. Dessa sjukdomar har en betydande inverkan på individens livskvalitet och bidrar ofta till ökad dödsrisk där komorbiditeter föreligger. LÄS MER

  5. 4. Dual RNA-seq analysis of gene co-expression and immune response mechanisms in chickens infected by Eimeria tenella

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Alma Hansen; [2023]
    Nyckelord :RNA-seq; Eimeria; bioinformatics; gene co-expression;

    Sammanfattning : Coccidiosis caused by Eimeria parasites is a worldwide problem, affecting chickens and leading to great losses in the poultry industry. Current vaccines are costly and non-optimal, and the parasite has developed resistance to the anticoccidials in use. LÄS MER

  7. 5. BAYESIAN HIERARCHICAL LINEAR MODELS FOR DIFFERENTIAL PROTEIN EXPRESSION ANALYSIS

    Master-uppsats, Uppsala universitet/Statistiska institutionen

    Författare :Siri Voghera; [2023]
    Nyckelord :Bayesian hierarchical modeling; differential protein expression analysis; proteomics;

    Sammanfattning : It is evident that the study of proteins is crucial for a deeper understanding of how drug treatments affect the body. However, differential protein expression analysis, which can be described as the method of finding which proteins are affected by a treatment, faces some major challenges. LÄS MER