Sökning: "Seurat"

Hittade 4 uppsatser innehållade ordet Seurat.

  1. 1. Single-cell RNA-seq mapping of chicken leukocytes : An investigation into single-cell transcriptomics as an alternative to traditional immunological methods within non-traditional model organisms

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Mikrobiologi och immunologi

    Författare :Matilda Maxwell; [2023]
    Nyckelord :Bioinformatics; scRNA-seq; avian; immunology; Seurat; leukocytes; chicken; gallus gallus; 10x genomics; PCA;

    Sammanfattning : The immune system is a complex infrastructure where many cells interact with each other and perform duties depending on their type and function. When using traditional immunological methods in studying non-traditional model organisms, such as birds, challenges arise. LÄS MER

  3. 2. Benchmarking of computational methods for Spatial Transcriptomics Data analysis

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Nima Taherpour; [2022]
    Nyckelord :Spatial Transcriptomics; Scanpy; Squidpy; Giotto; Seurat;

    Sammanfattning : Ökningen av sekvenseringsdata har skapat ett behov av att ta fram nya och flexibla analysmetoder för att kunna analysera datan. Många sekvenseringsteknologier har utvecklats genom åren, med olika syften och de är idag mer specialiserade. LÄS MER

  4. 3. Studying the Whole Through the Sum of its Parts: Comparing CD8+ Tumour Infiltrating Lymphocytes in Three Types of Human Carcinoma

    Kandidat-uppsats, Lunds universitet/Läkarutbildningen

    Författare :Gustav Christensson; [2020]
    Nyckelord :Cancer; immunotherapy; scRNA-seq; tumour-infiltrating lymphocyte; CD8 T cells; Medicine and Health Sciences;

    Sammanfattning : Background: Tumour-infiltrating lymphocytes (TILs) that persist in chronic infections gradually lose their effector functions and become “exhausted”. Immune checkpoint blockade is an emerging cancer treatment which aims to induce exhausted TILs into regaining their effector function to fight neoplastic cells. LÄS MER

  5. 4. Analysis of single cell RNA seq data to identify markers for subtyping of non-small cell lung cancer

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Veena K. Reddy; [2020]
    Nyckelord :;

    Sammanfattning : Single cell RNA technology is a recent technical advancement used to understand the cancertumorgenicity at single cell resolution. In this study we have analyzed the scRNA data from thenon-small cell lung cancer (NSCLC) dataset to facilitate the early identification of NSCLCsubtypes namely, squamous cell carcinoma (SCC) and adenocarcinoma (AC). LÄS MER