Sökning: "drug labels"

Visar resultat 1 - 5 av 14 uppsatser innehållade orden drug labels.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemi

    Författare :Maryam Dost; [2024]
    Nyckelord :Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Sammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER

  2. 2. Utilizing Transformers with Domain-Specific Pretraining and Active Learning to Enable Mining of Product Labels

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för beräkningsvetenskap

    Författare :Erik Norén; [2023]
    Nyckelord :Machine Learning; Natural Language Processing; NLP; BERT; Active Learning; AL; Pharmacovigilance; UMC; Uppsala Monitoring Centre; Structured Product Label; SPL; Transformers; Domain-Specific Pretraining; NER; Named Entity Recognition; Adverse Drug Reaction; ADR;

    Sammanfattning : Structured Product Labels (SPLs), the package inserts that accompany drugs governed by the Food and Drugs Administration (FDA), hold information about Adverse Drug Reactions (ADRs) that exists associated with drugs post-market. This information is valuable for actors working in the field of pharmacovigilance aiming to improve the safety of drugs. LÄS MER

  3. 3. Evaluating the Effectiveness of Active Learning Methods in Drug Repurposing

    Master-uppsats, Uppsala universitet/Institutionen för informationsteknologi

    Författare :Dalia Ortiz Pablo; [2022]
    Nyckelord :;

    Sammanfattning : Creating new drugs is an expensive process both in time and resources. Drug repurposing aims to find other uses for already approved medicines or clinical candidates to speed up the development of treatments; it can be done experimentally or computationally, with in silico approaches demonstrating many advantages. LÄS MER

  4. 4. A comparison between fully-supervised and self-supervised deep learning methods for tumour classification in digital pathology data

    Uppsats för yrkesexamina på avancerad nivå, Luleå tekniska universitet/Institutionen för system- och rymdteknik

    Författare :Elsa Jonsson; [2022]
    Nyckelord :AI; machine learning; digital pathology data; binary tumour classification;

    Sammanfattning : Whole Slide Images (WSIs) are digital scans containing rich pathology information. There are many available WSI datasets that can be used for a wide range of purposes such as diagnostic tasks and analysis, but the availability of labeled WSI datasets is very limited since the annotation process is both very costly and time consuming. LÄS MER

  5. 5. Risker med läkemedelsetiketter som används vid iordningställande på barnsjukhus : En undersökning av vilka etikettattribut som kan finnas på en framtida standard för etiketter inom barnsjukvården.

    Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaci

    Författare :Lina Suleiman Abdu; [2022]
    Nyckelord :;

    Sammanfattning : Risks with drug labels used in preparation of medicines in pediatric hospitals Background: Dosing and preparation of medicines can be challenging and risky. Therefore, drug labels are often used by healthcare personnel when preparing medicines for hospitalized patients. LÄS MER