Sökning: "protein NMR"

Visar resultat 1 - 5 av 22 uppsatser innehållade orden protein NMR.

1. 1. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

   Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

   Författare :Josef Getachew; [2023]
   Nyckelord :α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

   Sammanfattning : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. LÄS MER

3. 2. Synthesis of Fluorescent Analogues of FluoBar1 for Studying Protein Expression Rates in Living Cells

   Master-uppsats, Uppsala universitet/Organisk kemi

   Författare :Victor Hellgren; [2022]
   Nyckelord :;

   Sammanfattning : L-type voltage gated calcium channels are membrane bound ion channels that regulate the intracellular concentration of calcium ions as a response to changes in the membrane potential. They exist in four isoforms and recent studies have brought extra attention to the Cav1. LÄS MER

4. 3. Assignment of heteronuclear methyl-NMR spectrum of the 44 kDa protein MALT1 Casp-IgL3

   Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

   Författare :Maria Levkovets; [2022]
   Nyckelord :MALT1; NMR; methyl-NMR; protein NMR; Physics and Astronomy;

   Sammanfattning : Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) plays an important role in the immune pathway that controls the activation and proliferation of B and T cells. Dysregularization of this pathway leads to the development of highly aggressive lymphomas. LÄS MER

5. 4. Investigating Minor States of the Oncoprotein N-MYC, with Focus on Proline Cis/Trans Isomerisation using NMR Spectroscopy

   Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

   Författare :Frida Haugskott; [2021]
   Nyckelord :Myc; N-Myc; Intrinsically Disordered protein IDP ; Proline; cis-trans isomerisation; minor conformation; NMR; cancer;

   Sammanfattning : MYC is a family of three regulator genes that codes for transcription factors. Expression of Myc proteins from MYC genes is found to be deregulated in 70 % of all cancer forms. The three human homologs C-Myc, N-Myc and L-Myc are mainly associated with cancer in the lymphatic system, nerve tissues and lung cancer, respectively. LÄS MER

7. 5. Purification Methods for Solid-State NMR Analysis of Influenza A M2[18-60]

   Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

   Författare :Maxine Gripberg; [2021]
   Nyckelord :Solid-state NMR; Influenza A; M2 proton channel; Biophysical chemistry; Biology and Life Sciences; Technology and Engineering; Chemistry;

   Sammanfattning : With viral infections becoming an ever-increasing health problem in the world, the study of viral proteins is a cornerstone for understanding and preventing future pandemics. The following work shows the purification and structural characterization of the Influenza A M2 proton channel through solid-state NMR (ssNMR). LÄS MER