Sökning: "tissue specific gene expression"
Visar resultat 1 - 5 av 21 uppsatser innehållade orden tissue specific gene expression.
1. How molecular diagnostics based on gene expressions can improve diagnostics in Sarcoma
Kandidat-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknikSammanfattning : Sarcoma, a rare and heterogeneous cancer type, present significant diagnostic challenges due to its numerous subtypes. Molecular diagnostics and machine learning models have emerged as promising tools to enhance sarcoma diagnosis. LÄS MER
2. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse
Master-uppsats, KTH/ProteinvetenskapSammanfattning : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. LÄS MER
3. Energy Landscapes for Early T Cell Development
Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisationSammanfattning : T cell lineage development from an early thymic progenitor involves programmed shutoff of progenitor gene expression, upregulation of T cell specification genes, and proliferation. This biological system has been deeply studied and a gene regulatory network (GRN) that can accurately describe the system has been presented. LÄS MER
4. Expression of AGBL1, DCPS, RUNX1 and PHYKPL in colorectal cancer
Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologiSammanfattning : Colorectal cancer is one of the deadliest cancer forms because of late detection. Biomarkers can be used as an indication of cancer and plays of late a great role in cancer care, there are however currently no specific biomarkers that can be used for early detection of colorectal cancer. LÄS MER
5. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles
Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisationSammanfattning : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. LÄS MER