Sökning: "Biofysikalisk Kemi"

Visar resultat 6 - 10 av 13 uppsatser innehållade orden Biofysikalisk Kemi.

1. 6. Purification Methods for Solid-State NMR Analysis of Influenza A M2[18-60]

   Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

   Författare :Maxine Gripberg; [2021]
   Nyckelord :Solid-state NMR; Influenza A; M2 proton channel; Biophysical chemistry; Biology and Life Sciences; Technology and Engineering; Chemistry;

   Sammanfattning : With viral infections becoming an ever-increasing health problem in the world, the study of viral proteins is a cornerstone for understanding and preventing future pandemics. The following work shows the purification and structural characterization of the Influenza A M2 proton channel through solid-state NMR (ssNMR). LÄS MER

3. 7. A Molecular Dynamics Simulation Study of the Protein Stability of Reteplase in Formulation with Various Excipients during Freeze-Drying Processing

   Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

   Författare :Gabriella Björkengren; [2021]
   Nyckelord :Biophysical chemistry; protein stability; molecular dynamics simulation; Chemistry;

   Sammanfattning : The purpose of this project was to investigate protein stabilization by formulation excipients during the process of freeze-drying using Molecular Dynamics (MD) simulation. A recombinant therapeutic protein, Reteplase, was used as a model and the study focused on a comparative analysis of two excipients, arginine and tranexamic acid (TXA), as included in commercially available formulations of Reteplase. LÄS MER

4. 8. The Effect of Using DMSO as a Cosolvent for Ligand Binding Studies

   Master-uppsats, Lunds universitet/Biofysikalisk kemi

   Författare :Simon Birgersson; [2019]
   Nyckelord :Galectins; Nuclear Magnetic Resonance; NMR; Biophysical Chemistry; Relaxation; CPMG; ITC; Biofysikalisk Kemi; Kärnmagnetisk resonans; Technology and Engineering; Chemistry; Biology and Life Sciences;

   Sammanfattning : DMSO sees common application as a solvent for studies of synthetic molecules in biological systems, in fields such as drug design. Despite this, the possibility and nature of solvent interactions with both synthetic ligand and their target macromolecules is widely unexamined. LÄS MER

5. 9. Collective behaviour in suspensions of pushers and pullers

   Master-uppsats, Lunds universitet/Biofysikalisk kemi

   Författare :Shan Anjum; [2019]
   Nyckelord :biophysics; active matter; collective motion; microswimmers; biohydrodynamics; non-equilibrium physics; low reynolds number physics; biophysical chemistry; biofysikalisk kemi; Physics and Astronomy; Chemistry; Technology and Engineering;

   Sammanfattning : Microswimmer is a term that denotes small selfpropelling agents, such as bacteria, algea or artificial robots. Depending on the flow field they set up they can be categorized into two classes: pushers (e.g. E. LÄS MER

7. 10. Constructing supported lipid bilayers from native cell membranes

   Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

   Författare :Tommy Dam; [2018]
   Nyckelord :T cells; Model membrane systems; Supported lipid bilayers; SLB; biophysical chemistry; biofysikalisk kemi; Chemistry;

   Sammanfattning : The aim of this MSc-project was to investigate whether it is possible to incorporate native cell membrane components from Jurkat T cells into supported lipid bilayers, SLBs, to produce a model membrane system better resembling the native cell membranes in T cells. The procedure of forming native-like SLBs (nSLB) was adapted from an existing protocol and is done through the deposition of hybrid vesicles onto a cleaned glass slide. LÄS MER