Sökning: "cell-cell interactions"

Visar resultat 1 - 5 av 8 uppsatser innehållade orden cell-cell interactions.

  1. 1. Computational prediction of cell-cell interactions in the brain-tumour microenvironment

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Paula Camargo Romera; [2023]
    Nyckelord :Cancer; Glioblastoma; Computational Biology; Bioinformatics; Microenvironment; Brain tumour; Interactions; Systems Biology;

    Sammanfattning : Glioblastoma is the fastest-growing, and the most common malignant brain tumour in adults. It is normally treated with surgery and radio- or chemotherapy, but the approximate life expectancy is of 15 months with a high probability of cancer recurring. Therefore, there is a need for decreasing its severity. LÄS MER

  3. 2. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Neuroonkologi och neurodegeneration

    Författare :Mathilda Stigenberg; [2023]
    Nyckelord :cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

    Sammanfattning : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. LÄS MER

  4. 3. Biophysical analysis of Immunotherapy and Cancer modeling

    Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Författare :Simon Tropp; [2022]
    Nyckelord :Immunotherapy; Cancer; Tumors; Immune cells; T cells; Cancer prognostics; Cancer models; Cell distribution; Physics and Astronomy;

    Sammanfattning : Accounting for 10 million deaths and 20 million new cases every year, cancer is one of the most common causes of death. The interest in trying to understand this lethal disease using mathematical models has increased steadily for many decades. Methods for boosting the immune system to better fight cancer (immunotherapy) have also been long present. LÄS MER

  5. 4. Identification of changes in biomarkers relevant for breast cancer biology occurring in a novel 3D-Biosilk model

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Emmy Ståhl; [2021]
    Nyckelord :3D-Biosilk; breast cancer; 3D cell culture; recombinant spider silk; ZO-1; 3D-Biosilk; bröstcancer; 3D cellkultur; rekombinant spindeltråd; ZO-1;

    Sammanfattning : Bröstcancer är den vanligaste formen av cancer som drabbar kvinnor. Det är en heterogen och komplex sjukdom som består av flera undergrupper, var och en med distinkt morfologi och kliniska implikationer [1]. För att modellera och studera cellbiologi, vävnadsmorfologi, molekylära mekanismer och läkemedels effekter används cellkulturer [2]. LÄS MER

  7. 5. Bacterial interactions across a porous membrane

    Master-uppsats, Lunds universitet/Tillämpad biokemi

    Författare :Malin Alsved; Karin Hjerpe; [2015]
    Nyckelord :tillämpad biokemi; applied biochemistry; Biology and Life Sciences; Chemistry;

    Sammanfattning : Deepening our knowledge about bacterial infections is of high priority in the work against antimicrobial resistance. Many infections are as well polymicrobial, and the different bacterial species are able to affect each other by cell-cell communication. LÄS MER