Sökning: "programmed cell death"

Visar resultat 6 - 10 av 17 uppsatser innehållade orden programmed cell death.

  1. 6. Investigation Of Human Cancer Immune Interaction Using In Vitro Assays

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Irineos Papakyriacou; [2020]
    Nyckelord :Cancer immunotherapy; nivolumab; durvalumab;

    Sammanfattning : Cancer immunotherapy, including immune checkpoint blocking antibodies are important components for treatment of patients with various types of cancer as they enhance the ability of the immune system to fight tumours. However, tumor cells have the ability to develop resistance to a variety of transitional therapies such as chemotherapy. LÄS MER

  3. 7. Construction of a fusion protein for anchoring the inflammatory receptor NLRP3 to the cell membrane

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Rebecca Ling; [2019]
    Nyckelord :NLRP3 inflammasome; Overlap PCR; Fusion Protein; LPI™ technology;

    Sammanfattning : The innate immune system are a cooperation of many components – receptors being one of them. Both membrane-bound and cytosolic receptors play a large role in the defence system against pathogens and danger. LÄS MER

  4. 8. Synthesis of 3-azido-2,4,6-tri-O-(4-methoxybenzyl)-3-deoxy-galactopyranoside

    Master-uppsats, Lunds universitet/Centrum för analys och syntes

    Författare :Esbjörn Reistad; [2019]
    Nyckelord :Medicinal chemistry; Cancer; macrocyclization; Organic chemistry; Chemistry;

    Sammanfattning : Galectin-3 is a protein that is involved in many physiological processes such as metastasis, T-cell regulation etc. which makes it a good drug target for the medicinal chemist. LÄS MER

  5. 9. Immunterapi vid cancer : är blockering av PD-1 en möjlig behandlingsmetod för hund?

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Sofia Tengstrand; [2017]
    Nyckelord :cancer; immunterapi; PD-1; PD-L1; hund; immunotherapy; dog;

    Sammanfattning : Programmed cell death protein 1 (PD-1) är en ko-inhiberande receptor som uttrycks på bland annat T-celler. Vid aktivering av T-celler leder interaktion mellan PD-1 och dess ligand, PD-L1, till att signalering från T-cellsreceptorn inhiberas och T-cellernas effektorfunktioner hämmas. LÄS MER

  7. 10. Towards the identification of Tudor SN interactome : cloning of putative interactors

    Kandidat-uppsats, SLU/Department of Plant Biology (from 140101)

    Författare :Pernilla Elander; [2015]
    Nyckelord :Tudor staphylococcal nuclease; cloning; stress granules; processing bodies; programmed cell death;

    Sammanfattning : Tudor staphylococcal nuclease (TSN) is a protein found associated with stress granules (SG) and processing bodies (PB) where it acts as a part of the plant stress response. In plants not much is known for TSN. This project serves as a starting point in our attempt to elucidate the physically interacting proteins of TSN. LÄS MER