Sökning: "Multiple Sequence Alignment"

Visar resultat 1 - 5 av 14 uppsatser innehållade orden Multiple Sequence Alignment.

  1. 1. Prediction of multiple conformational states of membrane proteins

    Master-uppsats, Linköpings universitet/Bioinformatik

    Författare :Tobias Thorén; [2024]
    Nyckelord :Bioinformatics; Protein prediction; AlphaFold;

    Sammanfattning : Predicting protein structures has long been an area of active research in the field ofbioinformatics. Great strides have recently been made in this area by googles DeepMindteam. They developed an AI called AlphaFold which is able to make the most accuratepredictions of protein structures as of date. LÄS MER

  3. 2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Samuel Eriksson Lidbrink; [2023]
    Nyckelord :AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Sammanfattning : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. LÄS MER

  4. 3. Predicting Protein Stability with Machine Learning

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Lucas Carlsson; [2023]
    Nyckelord :Protein Stability; Biophysical Chemistry; Thermodynamics; Machine Learning; Deep Learning; Protein Language Model; Biochemistry; Multiple Sequence Alignment; Bioinformatics; Biology and Life Sciences;

    Sammanfattning : Protein stability is a property of high importance and is of interest in a variety of fields. It determines if a protein has its native fold and can be of influence in certain diseases such as Parkinson's and Alzheimer's disease. LÄS MER

  5. 4. Development of a Python Pipeline for the Analysis of Campylobacter

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Elvira Zetterberg; Evelina Andersson; Alma Nilsson; Moa Qvarnlöf; Corinne Olivero; Julia Sulyaeva; [2022]
    Nyckelord :Campylobacter; WGS; pipeline; sequence alignment; Illumina; ARIBA;

    Sammanfattning : Statens veterinärmedicinska anstalt, SVA, is a government agency that works for better animal and human health with a primary focus on infectious animal diseases. One of their projects involves tracking the spread of Campylobacter infection in broilers and the occurrence of antimicrobial resistance in these bacteria. LÄS MER

  7. 5. Evaluation and implementation of quality control parameters for genome-wide DNA methylome sequencing

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Sara Ekberg; [2022]
    Nyckelord :;

    Sammanfattning : Epigenomics is the study of modifications to the genetic material without changes to the DNA sequence, one such modification is methylation of nucleotides. DNA methylation is associated with gene regulation and is studied in a variety of fields such as cancer and ageing. LÄS MER