Sökning: "large-scale chromatography"

Visar resultat 1 - 5 av 13 uppsatser innehållade orden large-scale chromatography.

  1. 1. Navigating Large-Scale Plasmid DNA Purification : A Recommendation of Current and Future Downstream Purification Solutions

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Matilda Eriksson; Alva Wells; Maria Frey; Lisa Johansson; Gabriel Pettersson; David Sjöberg; [2023]
    Nyckelord :Plasmid purification; pDNA; large-scale chromatography;

    Sammanfattning : Previous small-scale methods for plasmid DNA (pDNA) purification fail to meet theindustry’s demand for sufficient quantities. Greater volumes of bacterial lysates are a consequence of larger volumetric fermentations and traditional large-scale down-stream purification processes have some disadvantages and limitations. LÄS MER

  3. 2. Study of yield variation in a pharmaceutical manufacturing process and optimization of purification subsection : By a design of experiments study of the production parameters and a laboratory study of the purification step

    Master-uppsats, Karlstads universitet/Fakulteten för hälsa, natur- och teknikvetenskap (from 2013)

    Författare :Sandra Lord; [2022]
    Nyckelord :Yield variations; activated carbon; pharmaceutical industry; purification; design of experiments; optimization; Utbytesvariation; aktivt kol; läkemedelsindustrin; reningssteg; experimentell design; optimering;

    Sammanfattning : The product R1-MR2E is an ester formed from an esterification of a carboxylic acid and an alcohol at Cambrex Karlskoga AB. The production of the intermediate R1-MR2E is a large-scale production and there are two main objectives and two sub-objectives that this project aims to study of the manufacturing. LÄS MER

  4. 3. Sorption of novel side-chain fluorinated polymers to sediment - the impact of pH

    Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Hanna Erléus; [2022]
    Nyckelord :Scotchgard™; sorption; sediment; pH; side-chain fluorinated polymer surfactants; Lake Hjälmaren.;

    Sammanfattning : Fluorinated compounds are produced on a large scale and their releases are contaminating the environment. Among these are side-chain fluorinated polymers found in technical mixtures of Scotchgard™, which are used as surfactants in fabric coating. LÄS MER

  5. 4. Discontinuous Galerkin Method for Liquid Chromatography Modelling

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik

    Författare :Sara Culligan; [2022]
    Nyckelord :;

    Sammanfattning : Chromatography is a separation technique used predominantly by the medical industry in purification and extraction of components in a solution. The setup is a column filled with resin particles where a solution of two components is filtered and separated due to different rates of interaction with the resin particles. LÄS MER

  7. 5. Double-layer vs single-layer cryogels as a dye affinity chromatography column, comparison study

    Master-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Thi Hoai Thu Trinh; [2022]
    Nyckelord :dye-affinity chromatography; single-layer cryogels; double-layer cryogels; protein purification; bovine serum albumin; biochemistry; Chemistry;

    Sammanfattning : Dye affinity chromatography is one of the chromatography techniques which uses dye as a ligand for protein purification. In this study, single-layer poly(acrylamide-allyl glycidyl ether) cryogel was prepared, which contains free epoxy groups at sub-zero temperature. LÄS MER