Sökning: "myeloid"

Visar resultat 1 - 5 av 35 uppsatser innehållade ordet myeloid.

  1. 1. Systematic Multi-Parametric Analysis of Acute Myeloid Leukemia (AML) Flow Cytometry Drug Screens using Flowty

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Augusta Jensen; [2023]
    Nyckelord :Acute myeloid leukemia; AML; cellular subpopulations; data analysis; precision medicine; Flowty; applied microbiology; Biology and Life Sciences;

    Sammanfattning : Acute myeloid leukemia (AML) is a heterogeneous disease, making it difficult to treat. The standard treatment is intensive chemotherapy and has not changed in 40 years. However, recently new drugs and as less intensive treatment regimens have been approved in the US and in Europe. However. LÄS MER

  3. 2. Comparing dropout regularization algorithms for convolutional neural networks identifying malignant cells for diagnosis of leukemia

    Kandidat-uppsats, Uppsala universitet/Statistiska institutionen

    Författare :Hampus Engström; Alexander Koutakis; [2023]
    Nyckelord :classification; Bernoulli; Gaussian; spatial; machine learning; cancer; myeloid; myeloproliferative neoplasms;

    Sammanfattning : Fast and high quality classifications of cells inflicted with malignant mutations is essential for diagnosing patients with different forms of leukemia, to quickly be able give patients the crucial care they need. Convolutional neural networks (CNNs) can be trained and used for this purpose. LÄS MER

  4. 3. Method development of magnetic cell isolation and DNA extraction of small cell populations from Ficoll-separated hematopoietic cells

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Dominika Debowska; [2023]
    Nyckelord :Clonal haematopoiesis of indeterminate potential CHIP ; hematopoietic stem cell; automated cell separation; silica-membrane-based nucleic acid purification.;

    Sammanfattning : Clonal haematopoiesis of indeterminate potential, or CHIP are a family of mutations present in the general population. CHIP-mutations are prevalent in the haematopoietic stem cells and in the more mature cell populations, T-lymphocytes, B-lymphocytes and myeloid cells (CD3+, CD19+ and CD33+ cells) in blood. LÄS MER

  5. 4. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model

    Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Emilie Allentoft Schousboe; [2023]
    Nyckelord :3D models; imiquimod; Langerhans cells; MUTZ-3 cell line; pro-inflammatory cytokines; psoriasis;

    Sammanfattning : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. LÄS MER

  7. 5. Patienters upplevelser av diagnos och behandling vid akut myeloisk leukemi : En kvalitativ litteraturöversikt

    M1-uppsats, Jönköping University/HHJ, Avd. för omvårdnad

    Författare :Elvira Johansson; Elenore Åström; [2023]
    Nyckelord :Cancer; Cytostatic treatment; Person-centred care; stem cell transplantation; Cancer; cytostatikabehandling; personcentrerad vård; stamcellstransplantation;

    Sammanfattning : Titel: Patienters upplevelser av diagnos och behandling vid akut myeloisk leukemi    Bakgrund: Akut myeloisk leukemi (AML) är den vanligaste formen av akut leukemi. Behandlingen och symtomen är påfrestande och långvariga, vilket inverkar på patienters livskvalitet. LÄS MER