Sökning: "bioinformatics"

Visar resultat 26 - 30 av 187 uppsatser innehållade ordet bioinformatics.

  1. 26. Detecting structural variants in the DNA of the inbred Scandinavian wolf

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Lars Huson; [2023]
    Nyckelord :animal; animal population; bioinformatics; biological sciences; biology; Canis lupus; CNV; conservation genetics; conservation genomics; copy-number variation; DNA; endangered population; endangered species; evolution; evolutionary biology; extinction; genetic diversity; genetics; genetic variation; genomes; genomics; grey wolf; inbreeding; inbreeding depression; indel; mutation; pedigree; population genetics; population genomics; Scandinavia; smoove; snakemake; structural variant; SV; wolf; wolves;

    Sammanfattning : Only 40 years ago, just three individuals made the journey from Finland/Russia to found the current wolf population in the southwest of Sweden. This population, that to this date descends from less than 10 founders, has a substantial increased extinction risk due to inbreeding. LÄS MER

  3. 27. Improving Usability of Bioinformatics Software with an Integrated Web Tool System for Cancer Diagnostics

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Solbritt Gateman; [2023]
    Nyckelord :Web development; bioinformatics pipelines; precision medicine; user-centred design; interface design;

    Sammanfattning : Precision cancer medicine is an area of research that involves complex bioinformatics software for the clinical analysis pipelines that sequencing data is passed through. A research team at Karolinska Institutet (KI) is running clinical trials to test new methods of precision cancer medicine and is working on creating a new web application that will be integrated with their two existing applications to aid bioinformaticians in their work of running pipelines and producing clinical reports for the hospitals. LÄS MER

  4. 28. Microbial diversity in Swedish breeds of sheep analysed by amplicon based sequencing

    Master-uppsats, SLU/Dept. of Anatomy, Physiology and Biochemistry

    Författare :Farzana Nazir; [2023]
    Nyckelord :Ruminants; Microbiome; NGS; Bioinformatics; Statistical Analysis; Metagenomics; Data Analysis;

    Sammanfattning : The gastrointestinal tract (GIT) of ruminants have divergent type of microbiome provides favourable environment for their growth. In many species, these microbiome considered as important source of assessing animal health & welfare. LÄS MER

  5. 29. Computational detection of human papilloma virus in the cervical cancer genome

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Hope Omoghene; [2023]
    Nyckelord :VirusFinder2; HPViewer; VirusSeq; HPV; Bioinformatics; Cervical cancer;

    Sammanfattning : Global research and development have witnessed new horizons in technological advancements, especially in the use of new-generation bioinformatic tools to solve human needs. Cervical cancer, caused by a sexually transmitted virus like human papillomavirus (HPV), is one of the most common cancers threatening women's health. LÄS MER

  7. 30. Messing With The Gap: On The Modality Gap Phenomenon In Multimodal Contrastive Representation Learning

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Industriell teknik

    Författare :Mohammad Al-Jaff; [2023]
    Nyckelord :Multimodal machine learning; Representation learning; Self-supervised learning; contrastive learning; computer vision; computational biology; bioinformatics;

    Sammanfattning : In machine learning, a sub-field of computer science, a two-tower architecture model is a specialised type of neural network model that encodes paired data from different modalities (like text and images, sound and video, or proteomics and gene expression profiles) into a shared latent representation space. However, when training these models using a specific contrastive loss function, known as the multimodalinfoNCE loss, seems to often lead to a unique geometric phenomenon known as the modality gap. LÄS MER