Sökning: "molecules"

Visar resultat 6 - 10 av 623 uppsatser innehållade ordet molecules.

  1. 6. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemi

    Författare :Maryam Dost; [2024]
    Nyckelord :Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Sammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER

  3. 7. Effects of early exposure to fluoxetine on behavioural development in zebrafish

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Moa Forssten; [2024]
    Nyckelord :Fluoxetine; zebrafish; development; behaviour;

    Sammanfattning : Many pharmaceuticals are stable molecules and after human excretion they enter the wastewater facilities where roughly 60 % is removed. The remaining residues will affect the concentration in close by streams and at the effluent, where fish like to spawn. Therefore, the development and behaviour of aquatic life is potentially at risk. LÄS MER

  4. 8. Quantum Optical Description of High-order Harmonic Generation

    Master-uppsats, Lunds universitet/Atomfysik; Lunds universitet/Fysiska institutionen

    Författare :Isabel Moreno; [2024]
    Nyckelord :Physics and Astronomy;

    Sammanfattning : High-order Harmonic Generation (HHG) is a highly non-linear process in which an atom interacts with a strong laser field. The laser field lowers the atomic potential barrier allowing bound electrons to escape into the continuum through tunnel ionization, propagate, and, with some probability, recombine with the parent ion. LÄS MER

  5. 9. Leveraging CNN for Automated Peak Picking in Untargeted Metabolomics without Parameter Dependencies

    Master-uppsats, Göteborgs universitet/Institutionen för data- och informationsteknik

    Författare :Vivian Wang; Lidia Yalew; [2023-10-19]
    Nyckelord :Deep learning; Convolutional neural network; LC-MS; Peak Detection; Metabolomics; Faster R-CNN;

    Sammanfattning : Metabolomics is a scientific discipline that involves the thorough analysis of small molecules, known as metabolites, found within a biological system. Furthermore, liquid chromatography-mass spectrometry (LC-MS) is a commonly used analytical technique in metabolomics for analysing biological samples due to its broad coverage of the measurable metabolome. LÄS MER

  7. 10. Predicting Chemical-Gene Interactions

    Master-uppsats, Göteborgs universitet / Institutionen för biologi och miljövetenskap

    Författare :Ali Chishti; [2023-08-04]
    Nyckelord :Pesticides; Small streams; Prediction modelling; Chemical-protein-gene interactions; Aquatic organisms;

    Sammanfattning : Pesticide use in agriculture has become a growing concern as it can have detrimental effects on the environment. The excessive use of these chemicals often leads to them seeping into nearby water bodies, causing harm to aquatic organisms. LÄS MER