Sökning: "Syntetiskt DNA"

Hittade 3 uppsatser innehållade orden Syntetiskt DNA.

1. 1. Recombinant Expression of Novel Wild Type Oat Hemoglobins in Escherichia Coli

   Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

   Författare :Frank Rummukainen; [2022]
   Nyckelord :Recombinant technology; Protein expression; Hemoglobin; Phytoglobin; Escherichia coli; Oat; Avena sativa; Heme; Iron; Biosynthesis; Transcription; qPCR; SDS-PAGE; Fermentation; Recombination; Applied Biochemistry; Biology and Life Sciences;

   Sammanfattning : Hemoglobin is a protein transporting oxygen through our bloodstreams and is as such essential for aerobic life. Hemoglobins also exist in plants, with a wide variety of functions other than oxygen transport. LÄS MER

3. 2. Simulations of polymer solutions displaying a lower critical solution temperature

   Kandidat-uppsats, Lunds universitet/Kemiska institutionen

   Författare :Sandra Larsson; [2018]
   Nyckelord :Monte Carlo simulations; polymer solutions; lower critical solution temperature; thermoresponsive polymers; LCST; theoretical chemistry; teoretisk kemi; Chemistry;

   Sammanfattning : Thermoresponsive polymers with a lower critical solution temperature, LCST, have attracted interest in the development of new ``smart materials'', which change properties in response to external stimuli. Polymers with an LCST near physiological temperatures are especially relevant in biomedical applications, most notably perhaps in drug delivery systems. LÄS MER

4. 3. Modeling the intronic regulation of Alternative Splicing using Deep Convolutional Neural Nets

   Master-uppsats, KTH/Skolan för datavetenskap och kommunikation (CSC)

   Författare :Johannes Linder; [2015]
   Nyckelord :Machine Learning; Deep Learning; CNN; CNNs; Convolutional Neural Networks; Convolutional Neural Nets; Neural Networks; Neural Nets; Synthetic Biology; Alternative Splicing; AS; Splicing; DNA Regulation; Synthetic DNA; Massively Parallel Library; Maskinlärning; CNN; CNNs; Convolutional Neural Networks; Convolutional Neural Nets; Faltning; Neurala Nätverk; Neurala Nät; Syntetisk Biologi; Alternativ Splicing; Splicing; AS; DNA; Massivt Parallellt Bibliotek; Syntetiskt DNA;

   Sammanfattning : This paper investigates the use of deep Convolutional Neural Networks for modeling the intronic regulation of Alternative Splicing on the basis of DNA sequence. By training the CNN on massively parallel synthetic DNA libraries of Alternative 5'-splicing and Alternatively Skipped exon events, the model is capable of predicting the relative abundance of alternatively spliced mRNA isoforms on held-out library data to a very high accuracy (R2 = 0. LÄS MER