Sökning: "enhancer"

Visar resultat 11 - 15 av 55 uppsatser innehållade ordet enhancer.

  1. 11. Validation of enhancer variants modulating haematological toxicity reactions

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Zandra Norberg; [2022]
    Nyckelord :Chemotherapy; haematological toxicity reaction; enhancer variants; CRISPRi; K562; Cytostatika; hematologiska toxicitetsreaktioner; enhancer-varianter; CRISPRi; K562;

    Sammanfattning : Omkring 20 miljoner nya cancerfall inträffar över hela världen varje år, och under 2020 uppskattades det att 10 miljoner dödsfall var förknippade med cancer. En av de vanligaste behandlingarna för cancer är cytostatika (cellgifter) som angriper alla snabbväxande celler. LÄS MER

  3. 12. Bitcoin as an enhancer of performance in an All Weather inspired portfolio

    Kandidat-uppsats, Lunds universitet/Nationalekonomiska institutionen

    Författare :Kim Ottosson; [2021]
    Nyckelord :Sharpe Ratio; Modern Portfolio Theory; Bitcoin; Treynor Measure; Optimization; Business and Economics;

    Sammanfattning : The thesis employs a number of tools originating from the field of Modern Portfolio Theory to assess the appropriate weight of Bitcoin in addition to several assets commonly found in the All-Weather Portfolio. Utilizing Sharpe Ratio optimization, the thesis compares two main portfolios to determine if the inclusion of Bitcoin can improve the performance and risk-return ratio of an optimized All Weather Portfolio. LÄS MER

  4. 13. Effektivitet och säkerhet av tricykliska antidepressiva och selektiva serotonin-återupptagshämmare vid behandling av irritabel tarmsyndrom (IBS)

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Mustafa Muatasim; [2021]
    Nyckelord :Irritable bowel syndrome; IBS; bowel functional disorder; tricyclic antidepressants; Selective serotonin reuptake inhibitors; SSRI; Känslig tarm; irritabel tarm; irriterad tarm; IBS; tarmsyndrom; tricykliska antidepressiva; TCA; Selektiva serotonin återupptagshämmare; SSRI;

    Sammanfattning : Irritable bowel syndrome (IBS) is a functional disorder that affects the gastrointestinal tract and especially the large intestine. The pathogenesis of the disease is not fully understood, for that reason there is still no cure and current therapy focuses on symptom relief. LÄS MER

  5. 14. Investigation and Optimization of Small-Scale Fecal Management : As a product from dry toilet solutions in off-grid Swedish holiday homes

    Master-uppsats, KTH/Skolan för industriell teknik och management (ITM)

    Författare :ELLEN DANIELSSON; CHRISTOPHER LEKSTRÖM; [2021]
    Nyckelord :Latrine compost; Feces; Composting process; Product development; Prototyping; Product design; User-centered design; Human-centered design; Circular economy; System investigation; Sustainable development; Latrinkompost; Fekalier; Komposteringsprocess; Produktutveckling; Prototyp; Produktdesign; Användarcentrerad design; Cirkulär ekonomi; Systemundersökning; Hållbar utveckling;

    Sammanfattning : In off-grid holiday homes, alternative toilet solutions are needed. There is a wide range of dry toilet systems, where urine-diverting systems and incineration toilets are common solutions. Urine-diverting dry toilets require that users need to manage generated fecal fractions. LÄS MER

  7. 15. CUSTOMIZED QUANTIFICATION OF HOST CELL PROTEIN WITH BIO-LAYER INTERFEROMETRY

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Eva Sjöblom; [2020]
    Nyckelord :BLI; HCP; CHO; yeast; host cell protein; bio-layer interferometry; immunoassays; quantification; chinese hamster ovary; ELISA; applied microbiology; teknisk mikrobiologi; Biology and Life Sciences; Technology and Engineering;

    Sammanfattning : Host cell protein (HCP) is quantified in the purification steps of biopharmaceutical production and is part of ensuring the purity of the final drug product. The gold standard method for HCP quantification is enzyme-linked immunosorbent assay (ELISA), but a new approach is proposed here with fully customized bio-layer interferometry assays for yeast and chinese hamster ovary (CHO) cells. LÄS MER