Sökning: "combinatorial synthesis"
Hittade 5 uppsatser innehållade orden combinatorial synthesis.
1. Training Machine Learning-based QSAR models with Conformal Prediction on Experimental Data from DNA-Encoded Chemical Libraries
Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskapSammanfattning : DNA-encoded chemical libraries (DEL) allows an exhaustive chemical space sampling with a large-scale data consisting of compounds produced through combinatorial synthesis. This novel technology was utilized in the early drug discovery stages for robust hit identification and lead optimization. LÄS MER
2. Fragment screening using WAC towards new SMARCA4 inhibitors
Master-uppsats, Lunds universitet/Centrum för analys och syntesSammanfattning : The drug discovery and development process has changed dramatically during the last decades and the growth of more efficient techniques as high throughput screening combined with combinatorial synthesis using amino acids and carboxylic acids on solid support makes it possible to investigate the affinity of molecules towards a biological target. Fragment based drug discovery (FBDD) has been implemented into different techniques with purpose of discovering new drugs. LÄS MER
3. Developing a Combinatorial Synthesis Database Tool
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Fasta tillståndets elektronikSammanfattning : Thin-film solar cell research is central to the electricity production of the near future. Photovoltaic technologies based on silicon have a significant portion of the global market and installed capacity. LÄS MER
4. Synthesis of solid solution TiBN coatings by cathodic arc evaporation
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Tillämpad materialvetenskapSammanfattning : The present work is aimed at determining the conditions for which synthesis of coatings composed of solid solution TiBN is possible using cathodic arc evaporation, a member of the physical vapor deposition family of coating techniques. Such coatings are interesting from a machining point of view because they have previously been shown to exhibit excellent tribological properties at elevated temperatures. LÄS MER
5. Synthesis of thin films of the Olivines Fe2SiS4 and Mn2SiS4 by magnetron sputtering and annealing
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Fasta tillståndets elektronikSammanfattning : The photovoltaic industry attracts a lot of interest from researchers worldwide due to active integration of the solar cells. The main idea here is to convert solar energy into electricity. One type of solar cell that shows potential in replacing today’s crystalline silicon cells is the thin film solar cell (TFSC). LÄS MER